• MEBO与生肌玉红膏治疗压迫性溃疡的临床对照观察
  • Clinical Control Observation of MEBO Ointment and Shengji Yuhong Ointment in the Treatment of Pressure Ulcers
  • 杜林海,张俊会,张学军,邵建阁.MEBO与生肌玉红膏治疗压迫性溃疡的临床对照观察[J].中国烧伤创疡杂志,2012,24(1):55~57.
    DOI:10.3969/j.issn.1001-0726.[year].[issue].[sequence]
    中文关键词:  MEBO Ointment  Shengji Yuhong Ointment  Pressure ulcer  Skin regeneration  Wound healing
    英文关键词:
    基金项目:
    作者单位
    杜林海 056500 河北 邯郸河北省邯郸市磁县中医院外科 
    张俊会 056500 河北 邯郸河北省邯郸市磁县中医院外科 
    张学军 056500 河北 邯郸河北省邯郸市磁县中医院外科 
    邵建阁 056500 河北 邯郸河北省邯郸市磁县中医院外科 
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    中文摘要:
          目的 比较湿润烧伤膏(MEBO)、表皮细胞生长因子(EGF)对自体微粒皮种植修复肉芽创面的临床疗效。方法 选取中老年糖尿病、瘫痪、严重全身营养不良的38例患者,其肉芽创面面积大于5cm2,按取皮面积∶创面面积=1∶20~30的比例种植自体微粒皮,将38例患者随机分为两组,治疗组15例(MEBO组),对照组23例(EGF组),分别用MEBO和EGF换药治疗至创面愈合,观察创面皮岛修复情况及愈合时间。结果肉芽创面经自体微粒皮种植术治疗后,应用MEBO和EGF治疗都能使其愈合,但治疗组(MEBO组) 的创面愈合率高于对照组(EGF组);MEBO组创面生长出皮岛以及愈合所需时间较EGF组明显缩短(P<001)。结论肉芽创面经自体微粒皮种植术治疗后,应用MEBO治疗较EGF更能有效地促进创面修复。
    英文摘要:
          Objective: To comparatively observe the clinical effect of the external use of MEBO Ointment and Shengji Yuhong Ointment in treating pressure ulcers. Methods: 54 patients with 84 pressure ulcers were divided into a treatment group and a control group by a random number table. MEBO Ointment was used in the treatment group while Shengji Yuhong Ointment was used in the control group. Wound healing outcomes in two groups were collected for comparison and summarization. Results: After the comparison, the data in terms of wound surface improvement, granulation growth and healing time collected in the treatment group was obviously superior to that in control group. Conclusion: MEBO Ointment is effective in removing necrotic tissues, promoting the growth of granulation tissue and skin, and accelerating the healing of pressure ulcers.