| 付子俊.MEBO治疗皮肤癌的临床体会[J].中国烧伤创疡杂志,2012,24(4):313. |
| DOI：10.3969/j.issn.1001-0726.2012.4.018 |
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| 中文摘要: |
| 目的 了解应用湿润烧伤膏(MEBO) 治疗皮肤癌的疗效。方法 随机选择56 例皮肤癌病例, 均在局部浸润麻醉后单纯切除原发癌灶, 不缝合创面, 直接外涂MEBO 2 mm ~ 3 mm, 无菌纱布包扎治疗, 每日换药2次。分别在手术当时、术后7 d ~10 d、创面基本愈合时取基底部组织及手术切除的肿瘤组织进行病理活检。结果56 例创面均愈合, 创面基本愈合时基底部组织的病理活检均显示慢性肉芽肿伴感染。结论 单纯手术切除癌灶后,外用MEBO 治疗创面, 创面出血少, 患者无痛苦, 并可避免扩大根治性手术对机体的再损伤, 通过换药治疗后, 创面无损伤愈合, 并可无损伤地抑制残留肿瘤组织的生长, 该类患者最终都是以炎性肉芽组织的形式愈合, 这为皮肤癌的治疗提供了一种简单有效的新方法。 |
| 英文摘要: |
| Objective To explore the effect of MEBO in treating skin cancer. Methods Randomly choose 56 cases
of skin cancer, and excise primary cancer tissue under local infiltration anaesthesia without suture. Apply MEBO directly on
the wound with 2mm -3 mm thickness and bandage it with sterile gauze. Change dressing twice a day. Take pathological biopsy
of the excised cancer tissue as well as basilar tissue taken during surgery, 7 -10 day post surgery and at early wound healing
stage. Results All the 56 cases healed, and chronic swelling of granulation tissue and infection were shown by the pathological
biopsy of basilar tissue at early wound healing stage. Conclusion After resection of foci alone, topical use of MEBO in the
treatment of wounds can reduce bleeding and pain, and avoid the further injury on the body by the radical surgery. After the
dressing change of MEBO treatment, the wound heals without injury, and the growth of the residual tumor tissue can be inhibited
without injury to the healthy tissue. All the patients are ultimately healed in the form of inflammatory granulation tissue,
which provides a simple and effective new method for the treatment of skin cancer. |
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