| 王 军,刘 岩.原位再生疗法治疗复合伤患者烧伤创面疗效观察[J].中国烧伤创疡杂志,2013,25(2):102~104. |
| DOI：10.3969/j.issn.1001-0726.2013.2.004 |
| 中文关键词: 湿润烧伤膏 皮肤原位再生疗法 复合伤 烧伤创面 |
| 英文关键词:MEBO In situ skin regenerative restoration therapy Compound injury Burned wounds |
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| 中文摘要: |
| 目的 观察评估皮肤原位再生疗法治疗复合伤患者烧伤创面的疗效和安全性。方法 41例复合伤患者在积极治疗合并伤的同时，对烧伤创面采用皮肤原位再生疗法治疗，同时给予抗感染、抗休克及营养支持等对症治疗，观察创面治疗效果。结果 除1例患者因严重颅脑损伤于治疗第3天死亡，1例患者在治疗第2天时死于创伤性休克外，余39例患者均康复出院。平均愈合时间：浅Ⅱ度创面为10.3d±1.9d，深Ⅱ度创面为19.8d±2.4d，Ⅲ度创面为32.5d±6.4d。15例深Ⅱ度烧伤患者中有3例患者创面愈合后留有轻度瘢痕，但不影响功能，余12例患者创面无明显瘢痕形成；治愈的39例患者中有11例患者创面愈合后遗留色素沉着；所有患者在治疗过程中均无明显疼痛及其他不良反应，且抗感染效果显著。结论 采用皮肤原位再生疗法治疗复合伤患者烧伤创面，能够减轻患者疼痛，预防感染，较好地保护与修复创面，解决复合伤创面在治疗时机上相互冲突的问题，为严重复合伤患者烧伤创面的治疗提供了一种新的疗法。 |
| 英文摘要: |
| Objective To observe and evaluate the curative effect and safety of in situ skin regenerative restoration therapy in treating compound burned wounds. Methods Burned wounds of forty-one patients with compound injuries were treated with in situ skin regenerative restoration therapy at the meantime of performing active treatments for compound injuries; in addition, some symptomatic treatments of anti-infection, anti-shock and nutrition support and etc. were used. The curative effects were observed. Results One patient died of severe craniocerebral injury on the third day of treatment, one patient died of traumatic shock on the second day of treatment, and the other 39 patients all recovered and were discharged from hospital. Of the fifteen patients with deep second-degree burns, three cases realized wound healing with mild scar formation not affecting function, while the other 12 cases realized wound healing without obvious scarring. Hyperpigmentation occurred in 11 cases out of the 39 healed patients. The mean healing times were 10.3 d士1.9 d, 19.8 d士2.4 d and 32.5 d士6.4 d for superficial second-degree wounds, deep second-degree wounds and third-degree wounds respectively. During the treatment course, no obvious pain or adverse reactions happened. The curative effect of anti-infection was significant. Conclusion The application of in situ skin regenerative restoration therapy to treat compound burned wounds can better protect and repair wounds and realize effects of anti-pain and anti-infection, solving the timing conflict problem in treating compound injuries, it therefore provides a new treatment approach for the patients with severe compound burned wounds. |
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