| 徐文举,李天宇.湿润烧伤膏与碱性成纤维细胞生长因子治疗小儿烧伤创面的疗效对比[J].中国烧伤创疡杂志,2014,(1):26~29. |
| DOI： |
| 中文关键词: 湿润烧伤膏 碱性成纤维细胞生长因子 小儿烧伤 深Ⅱ度烧伤 疗效对比 |
| 英文关键词:Moist Exposed Burn Ointment (MEBO) Basic Fibroblast Growth Factor Pediatric burn Deep Ⅱdegree burn Efficacy comparison |
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| 中文摘要: |
| 目的 探索促进小儿深Ⅱ度烧伤创面愈合的有效? 可靠? 易于推广的治疗方法? 方法 将60例患儿分为试验组(30例) 与对照组(30例)? 试验组: 患儿创面外用湿润烧伤膏(MEBO), 单层油纱覆盖, 每天换药1次; 对照组: 患儿创面外用碱性成纤维细胞生长因子(rb?bFGF), 单层油纱覆盖, 每天换药1次, 对比观察两组患儿创面愈合情况? 结果 试验组患儿创面坏死组织液化早? 脱落快, 治疗1周后仅有4例患儿创面培养带菌, 创面愈合时间为2~3周, 4例患儿创面愈后有色素沉着, 无瘢痕增生, 与对照组相比, 差异均具有明显的统计学意义? 结论 湿润烧伤膏治疗小儿烧伤创面的疗效优于rb?bFGF, 是一种治疗烧伤创面的有效药物, 且痛苦小? 费用低, 容易被患儿及家属接受, 易于推广? |
| 英文摘要: |
| Objective: To explore an effective, reliable and easy-to-popularize therapy of deep second degree pediatric burn wounds. Methods: Sixty burned children in hospital were randomly divided into two groups, 30 cases in each group. Experimental group was treated with Moist Exposed Burn Ointment (MEBO); control group was treated with basic fibroblast growth factor (rb-bFGF). All wounds were covered by single-layer oil gauze and dressing change was conducted once a day. Wound healing status was comparatively observed in two groups. Results: Earlier liquefaction and exfoliation of necrotic tissues at wound sites were found in experimental group, in which germs were found in culture of wound necrotic tissue of only four cases after 1 week treatment, wounds healed within 2-3 weeks, and four cases had pigmentation without scar hyperplasia after healing, which had statistical significance compared with that of control group. Conclusion: Moist Exposed Burn Ointment (MEBO) is superior to rb-bFGF in the treatment of pediatric burn wounds. Treatment with MEBO has better efficacy, less suffering and lower cost, thus it is easily accepted by patients and their guardians and popularized in clinical application. |
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