| 张向清.烧伤创面外用药物的临床应用现状[J].中国烧伤创疡杂志,2016,(3):192~196. |
| DOI： |
| 中文关键词: 烧伤 创面外用药物 磺胺嘧啶银 湿润烧伤膏 皮肤原位再生医疗技术 |
| 英文关键词:Burn External Medicine SD-AG MEBO Skin in situ regenerative medical technology |
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| 中文摘要: |
| 【摘要】外用药物治疗烧伤创面的历史久远，在20世纪中叶，我国引进了西方的烧伤治疗模式，将控制创面感染作为烧伤治疗的核心，外用磺胺嘧啶银（SD-Ag）可预防或控制感染，促使创面干燥，并为深度烧伤创面的切（削）痂手术治疗创造条件。但之后的研究发现，SD-Ag治疗烧伤的作用在逐渐减弱，单纯应用SD-Ag难以控制复杂类型的细菌感染。在烧伤治疗徘徊不前的困境下，20世纪70年代末，我国学者徐荣祥教授根据中国“理法方药”原理，发明了一种创面外用药物——湿润烧伤膏（Moist Exposed Burn Ointment，MEBO），实现了烧伤皮肤组织的原位再生修复，获得了举世瞩目的成就。笔者回顾了相关资料和研究成果，针对烧伤创面外用药物的临床应用现状作一综述，旨在进一步完善烧伤治疗体系。 |
| 英文摘要: |
| 【Abstract】Treating burns with external medicine has a long history. In the middle of the 20th century, the western model of treating burns was introduced into China, which focuses on wound infection control, uses externally SD-Ag to prevent or control infection and promote wound dryness, and prepares conditions for escharectomy in case of deep burns. However, the later studies revealed that SD-Ag is decreasingly effective in burn treatment and its application can’t control complicated bacterial infection. In the face of the stagnation of burn treatment, at the end of 1970s, Professor Rongxiang Xu, a Chinese scholar invented a new external medicine for treating wound —MEBO ( Moist Exposed Burn Ointment) based on the Chinese theory of “theory, methodology, prescription and medication” and achieved remarkable accomplishments by realizing the in situ regenerative restoration of burned skin tissues. The author made a summary of the status quo of the clinical application of external medicine in burn treatment by reviewing relevant literature and study outcomes, in order to perfect the burn treatment system. |
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