• 根除幽门螺杆菌感染与胃癌发病的研究进展
  • Progress of Study on the Eradication of Helicobacter Pylori Infection and Gastric Cancer
  • 史宗明,叶 晖,张学智.根除幽门螺杆菌感染与胃癌发病的研究进展[J].中国烧伤创疡杂志,2016,(4):278~281.
    DOI:
    中文关键词:  幽门螺杆菌  胃癌  癌前病变  根除  预防
    英文关键词:Helicobacter pylori  Gastric Cancer  Precancerosis  Eradication  Prevention
    基金项目:国家自然科学基金项目(项目编号:81473474)
    作者单位
    史宗明 北京大学第一医院中医、中西医结合科 
    叶 晖  
    张学智  
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    中文摘要:
          【摘要】幽门螺杆菌(Helicobacter pylori,H.pylori)感染是胃癌和癌前病变的重要始动因子,参与致病的因子包括毒力因子、癌基因和抑癌基因、黏附素等。根除H.pylori可延缓癌前病变进展,改善肠上皮化生,降低胃癌发病率。本文就近年来幽门螺杆菌与胃癌的相关性研究予以综述,旨在为胃癌的防治提供参考。
    英文摘要:
          【Abstract】Helicobacter pylori (H. pylori) infection is an important etiological factor of gastric carcinoma and precancerosis, and other factors involved include virulence factors, oncogene, antioncogene and adhesin, etc. Eradication of H. pylori can delay precancerous progression, improve the state of intestinal metaplasia, and lower the incidence of gastric cancer. This paper is to review studies of recent years on the association between H. pylori and gastric cancer, in order to provide references for the prevention and treatment of gastric cancer.