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烧伤病房装修对多重耐药铜绿假单胞菌的影响
Influence of Burn Ward Renovation on Multi⁃drug Resistant Pseudomonas Aeruginosa

孟进松,林国安,尚新志.烧伤病房装修对多重耐药铜绿假单胞菌的影响[J].中国烧伤创疡杂志,2016,(6):403~407.

DOI：

英文关键词:Burns Ward renovation Disinfection and isolation Multi⁃drug resistant pseudomonas aeruginosa Antibacterial agents

基金项目:

作者	单位
孟进松	解放军第159 医院烧伤中心
林国安
尚新志

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中文摘要:

【摘要】目的观察病房装修对减少多重耐药铜绿假单胞菌, 提高抗菌药物敏感性的效果?方法对比观察病房装修后解放军第159 医院烧伤中心2012 年3 月1 日- 2013 年4 月30 日收治的421 例患者与病房装修前2010 年1 月1 日-2011 年10 月29 日收治的458 例患者的创面分泌物细菌培养及药敏试验结果?结果细菌培养结果表明, 病房装修前患者多重耐药铜绿假单胞菌阳性率为9.8%, 对10 种抗菌药物敏感率均小于50.0%, 耐药性极高; 而病房装修后患者多重耐药铜绿假单胞菌阳性率为6.6%, 抗菌药物敏感率均升高, 两组对比, P <0.01, 差异具有统计学意义?结论病房装修联合消毒隔离?病房轮流空置及控制抗菌药物应用等措施, 能明显降低烧伤病房多重耐药铜绿假单胞菌菌株数量, 提高该菌对抗菌药物的敏感率, 有利于预防烧伤患者多重耐药铜绿假单胞菌感染?

英文摘要:

【Abstract】 Objective To observe the effect of ward renovation on reducing multi?drug resistant pseudomonas aeruginosa and improving their sensibility to antibacterial agents. Methods The study enrolled 421 patients admitted into the Burn Center of the PLA 159 Hospital between March 1, 2012 and April 30, 2013 (after the ward renovation), and 458 patients admitted between January 1, 2010 and October 29, 2011 (before the ward renovation), and their results of bacterial culture and drug sensitive tests were observed and compared. Results The bacterial culture results showed the positive rate of multi?drug resistant pseudomonas aeruginosa in before?renovation patients was 9.8%, and their sensitivities to ten anti?bacterial agents were all lower than 50%, with very high drug resistance, while positive rate of multi?drug resistant pseudomonas aeruginosa in after?renovation patients was 6.6% and their sensitivities to anti?bacterial agents all increased,which revealed a statistically significant difference between the two groups of patients, P <0.01. Conclusion Ward renovation, in combination with disinfection and isolation, ward shifts and controlling the application of anti?bacterial agents,etc. , can significantly reduce the strain number of multi?drug resistant pseudomonas aeruginosa in burn wards and improve its sensitivity to anti?bacterial agents, being conducive to the infection prevention of multi?drug resistant pseudomonas aeruginosa in burn patients.