• 卡巴胆碱抗炎作用的研究进展
  • Research Advance in the Anti⁃inflammatory Effect of Carbachol
  • 蒋沁芳,廖 毅.卡巴胆碱抗炎作用的研究进展[J].中国烧伤创疡杂志,2016,(6):409~415.
    DOI:
    中文关键词:  卡巴胆碱  抗炎  胆碱能抗炎通路  综述
    英文关键词:Carbachol  Anti⁃inflammation  Cholinergic anti⁃inflammatory pathway  Review
    基金项目:
    作者单位
    蒋沁芳 西南医科大学附属医院整形烧伤外科 
    廖 毅  
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    中文摘要:
          【摘要】 卡巴胆碱(Carbamylcholine, Carbachol) 是一种人工合成的拟胆碱药, 其作用与生理性乙酰胆碱(Acetylcholine, ACh) 非常相似, 主要通过N 样胆碱能受体发挥作用?随着“胆碱能抗炎通路” 的提出, 越来越多的学者将其作为防治炎症反应的关键药物进行研究?本文将卡巴胆碱抗炎作用的研究进展予以综述, 旨在为胆碱能抗炎的研究者提供思路和帮助?
    英文摘要:
          【Abstract】 Carbachol, as a synthetic Cholinergic agent and with the exactly similar functions to physiological acetylcholine, plays its role by Nicotinic acetylcholine receptors (nAChRs). As the Cholinergic anti?inflammatory pathway is put forward, more and more scholars are studying it as a key drug to fight inflammation. This paper is to review the progress of research on the anti?inflammatory effects of Carbachol, with the purpose of providing ideas and help for researchers studying the cholinergic anti?inflammatory effect.