| 朱振风,高学美,武 霞.湿润烧伤膏联合龙血竭治疗头颈部肿瘤放射性皮肤损伤的应用研究[J].中国烧伤创疡杂志,2017,(3):225~227. |
| DOI： |
| 中文关键词: 湿润烧伤膏 龙血竭 放射治疗 放射性皮肤损伤 疗效 |
| 英文关键词:MEBO Longxuejie Radiation therapy Radioactive skin damage Clinical efficacy |
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| 中文摘要: |
| 目的 对比观察湿润烧伤膏联合龙血竭治疗头颈部肿瘤放射性皮肤损伤的临床疗效?方法 将2014 年10 月—2016 年10 月临沂市第三人民医院及临沂市中心医院肿瘤科收治的192 例头颈部肿瘤放射性皮肤损伤患者随机分为研究组(64 例)?对照1 组(64 例) 和对照2 组(64 例), 研究组患者皮损创面采用湿润烧伤膏联合龙血竭治疗; 对照1 组患者皮损创面单纯采用湿润烧伤膏治疗; 对照2 组患者皮损创面单纯采用龙血竭治疗?对比观察3 组患者的创面愈合时间及创面愈合效果?结果 3 组患者皮损创面全部愈合, 其中研究组患者皮损创面愈合时间为(6.2±0.6) d, 对照1 组患者皮损创面愈合时间为(9.0±0.4) d, 对照2 组患者皮损创面愈合时间为(10.6±0.8) d; 治疗过程中, 研究组无1 例患者中断放疗, 对照1 组有8 例患者中断放疗, 对照2 组有10 例患者中断放疗; 治疗7 d 后, 研究组治愈58 例?有效6 例?无效0 例; 对照1 组治愈45 例?有效8 例?无效11 例; 对照2 组治愈40 例?有效11 例?无效13 例?研究组患者皮损创面愈合时间?中断放疗例数及临床疗效分别与对照1 组及对照2 组对比, P 均<0.05, 差异具有统计学意义?结论 湿润烧伤膏联合龙血竭治疗头颈部肿瘤放射性皮肤损伤, 可明显缩短创面愈合时间, 缓解创面疼痛, 提高创面愈合效果, 且操作简便, 费用低廉, 值得临床推广应用? |
| 英文摘要: |
| Objective: To observe and compare the clinical efficacy of MEBO in combination with Longxuejie in the treatment of radioactive skin damage in patients with head and neck tumors. Methods: One hundred and ninety-two head-neck tumor patients with radioactive skin damage admitted into the Department of Oncology of Linyi Third People’s Hospital and Linyi Central Hospital between October 2014 and October 2016 were randomly divided into a study group (n=64), control group 1(n=64) and control group 2(n=64). The damage wounds in the study group was managed with MEBO combined with Longxuejie, that in the control group 1 was managed simply with MEBO while that in the control group 2 was managed simply with Longxuejie. The wound healing time and wound healing effects in the three groups were observed and compared. Results: All damaged skin wounds were completely healed in the three groups. The wound healing time in the study group was (6.2±0.6)d, that in the control group 1 was (9.0±0.4)d and that in the control group 2 was (10.6±0.8)d; During the treatment course, no patient in the study group discontinued the radiotherapy, 8 patients discontinued the radiotherapy in the control group 1 while 10 patients discontinued the radiotherapy in the control group 2. Seven days after the treatment, in the study group there were 58 patients cured, 6 effective and none ineffective; in the control group 1 there were 45 patients cured, 8 effective and 11 ineffective; while in the control group 2 there were 40 patients cured, 11 effective and 13 ineffective. The comparisons between the study group and the control group 1 or the control group 2 in terms of wound healing time, number of cases discontinued the radiotherapy and clinical efficacy all showed statistically significant differences (all P<0.05). Conclusion: MEBO in combination with Longxuejie in the treatment of radioactive skin damage in patients with head-neck tumors can remarkably shorten wound healing time, relieve patient’s pain and improve the wound healing effect, in addition to its simple-and-easy operation and low cost, deserving to be promoted in clinical practice. |
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