班 超,周文海.湿润烧伤膏治疗剥脱性唇炎疗效观察[J].中国烧伤创疡杂志,2017,(5):351~353. |
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中文关键词: 湿润烧伤膏 再生医疗技术 丁酸氢化可的松软膏 剥脱性唇炎 疗效 |
英文关键词:MEBO Regenerative medical technologies, Hydrocortisone butyrate ointment Exfoliative cheilitis Clinical effect |
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中文摘要: |
【摘要】 目的 对比观察湿润烧伤膏治疗剥脱性唇炎的临床疗效?方法 将2015 年12 月—2016 年11 月郑州大学附属洛阳中心医院皮肤性病科收治的46 例剥脱性唇炎患者随机分为试验组(24例) 与对照组(22例),其中试验组患者采用湿润烧伤膏治疗, 对照组患者采用丁酸氢化可的松软膏治疗, 对比观察两组患者的临床疗效?结果 试验组患者皮损创面痊愈时间为(12.50±1.02) d, 对照组患者皮损创面痊愈时间为(16.50±1.26) d, 两组对比, P <0.01, 差异具有统计学意义; 治疗20 d 后, 试验组患者中痊愈12 例, 显效10 例, 好转2 例, 有效率为91.67%, 对照组患者中痊愈6 例, 显效8 例, 好转6 例, 无效2 例, 有效率为63.64%, 两组对比, P <0.05, 差异具有统计学意义?结论 MEBO 治疗剥脱性唇炎, 可有效促进皮损创面的愈合, 疗效显著,且治疗过程中无明显不良反应, 安全性较高, 患者依从性较好, 值得临床推广应用? |
英文摘要: |
【Abstract】 Objective To observe the clinical effect of MEBO in the treatment of exfoliative cheilitis. Methods 46 patients with exfoliative cheilitis admitted to the Dermatology & STD Department of Affiliated Luoyang Central Hospital of Zhengzhou University between December 2015 and November 2016 were randomly divided into experimental group (24 cases) and the control group (22 cases). Patients in the experimental group were treated with MEBO while patients in the control group were treated with Hydrocortisone Butyrate Ointment. The clinical outcomes of the two groups were then observed and compared. Results Skin lesion healing time for patients in the experimental group was (12.50±1.02) d and skin lesion healing time for patients in the control group was (16.50±1.26) d. The comparison of the two groups showed statistically significant difference (p< 0.01); After 20 days of treatment, in experimental group, 12 patients were cured, 10 were markedly effective, 2 were effective and total effective rate was 91.67%. In control group, 6 patients were cured, 8 were markedly effective, 6 were effective, 2 were ineffective and the total effective rate was 63.64%. The comparison of the two groups showed statistically significant difference (p< 0.05). Conclusion MEBO can promote wound healing, and causes no significant adverse reactions in the treatment of exfoliative cheilitis. It should be promoted in clinical practice in that it is safe and patient compliance is good. |
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