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湿润烧伤膏治疗Wanger1～2级糖尿病足疗效观察
Observation on the Clinical Efficacy of Moist Exposed Burn Ointment (MEBO) in the Treatment of Diabetic Foot of Wagner Grade I-II

张丽艳,袁继龙.湿润烧伤膏治疗Wanger1～2级糖尿病足疗效观察[J].中国烧伤创疡杂志,2019,(2):101~104.

DOI：

英文关键词:MEBO Diabetic foot Fufang Huangbaiye Tuji Wound repair Clinical efficacy

基金项目:

作者	单位
张丽艳	中国人民解放军北部战区总医院烧伤科
袁继龙	辽宁省人民医院整形美容外科

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中文摘要:

【摘要】　目的　观察湿润烧伤膏治疗Wagner 1～2级糖尿病足的临床疗效。方法　选取2017年1月至2018年5月中国人民解放军北部战区总医院烧伤科收治的81例Wagner 1～2级糖尿病足患者作为研究对象，按照随机数表法将其随机分为湿润烧伤膏组（43例）和复方黄柏液涂剂组（38例），其中湿润烧伤膏组患者采用湿润烧伤膏治疗局部创面，复方黄柏液涂剂组患者采用复方黄柏液涂剂治疗局部创面，对比观察治疗第14、28天时两组患者的创面愈合情况。结果　治疗第14及28天，两组患者创面均明显缩小，且尤以湿润烧伤膏组缩小最为明显，两组对比， P均＜0.05，差异具有统计学意义；治疗第28天，湿润烧伤膏组患者中痊愈27例、显效15例、有效1例、痊愈率为62.8%，复方黄柏液涂剂组患者中痊愈12例、显效20例、有效6例、痊愈率为31.6%，两组对比， P＜0.05，差异具有统计学意义。结论　湿润烧伤膏可明显促进Wagner 1～2级糖尿病足创面的愈合，临床疗效肯定，值得推广应用。

英文摘要:

【Abstract】Objective: To observe the clinical efficacy of Moist Exposed Burn Ointment (MEBO) in the treatment of diabetic foot of Wagner grade I-II. Methods: Eighty-one patients with diabetic foot of Wagner grade I-II, admitted to the Burns Department of PLA General Hospital in Northern Theater between January 2017 and January 2018, were divided into MEBO group (43 patients) and Fufang Huangbaiye Tuji (Compound Phellodendron Lotion) group (huangbaiye group) (38 patients) according to the random number table. In the MEBO group, the local wounds of patients were treated with MEBO while the local wounds of patients in the Huangbaiye group were treated with Fufang Huangbaiye Tuji, and the wound healing condition on day 14 and 28 of treatment were observed and compared between the two groups. Results: On day 14 and 28 of treatment, the wounds in the two groups were all decreased in size, especially in the MEBO group, and the comparison of wound size decrease between the two groups showed statistically significant differences, P＜0.05. On day 28 of treatment, in the MEBO group 27 patients were cured, 15 patients presented marked treatment effectiveness, 1 patient showed effectiveness, and the cure rate was 62.8%, which showed statistically significant difference as compared with the corresponding 12 cured patients, 20 patients with marked treatment effectiveness, 6 patients with effectiveness and 31.6% as the cure rate in the Huangbaiye group, P＜0.05. Conclusion: In the treatment of diabetic foot of Wagner grade I-II, MEBO can effectively promote the wound healing and its clinical efficacy is definite, deserving to be promoted in clinical practice.