| 徐礼笑子,李 民.湿润烧伤膏治疗糖尿病合并足部Ⅱ度烫伤疗效观察[J].中国烧伤创疡杂志,2019,(2):113~116. |
| DOI： |
| 中文关键词: 湿润烧伤膏 重组牛碱性成纤维细胞生长因子 糖尿病 烫伤 疗效 |
| 英文关键词:MEBO rb-bFGF Diabetes Scald Clinical effect |
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| 中文摘要: |
| 【摘要】 目的 探讨湿润烧伤膏(moist exposed burn ointment，MEBO) 治疗糖尿病合并足部Ⅱ度烫伤的临床疗效。方法 回顾性分析南方医科大学附属南海医院烧伤整形外科2011年至2017年收治的符合纳入标准的69例糖尿病合并足部Ⅱ度烫伤患者的病历资料，根据治疗方法的不同将2015 年至2017 年收治并采用MEBO 治疗局部创面的34 例患者设为治疗组，2011 年至2014 年收治并采用重组牛碱性成纤维细胞生长因子(recombinant bovine basic fibroblast growth factor，rb-bFGF) 凝胶治疗局部创面的35 例患者设为对照组，对比分析两组患者的创面愈合效果及愈合时间。结果 治疗21 d 后，治疗组患者的显效率为76.47%?总有效率为94.12%，明显优于对照组患者的显效率28.57%?总有效率68.57%，两组对比，P<0.01，差异具有统计学意义; 最终两组患者创面均完全愈合，其中治疗组患者的创面愈合时间为(25.35±7.41) d，对照组患者的创面愈合时间(39.29±10.78) d，两组对比，P<0.01，差异具有统计学意义。结论 MEBO可有效促进糖尿病合并足部Ⅱ度烫伤患者的创面愈合，提高创面愈合效果，缩短创面愈合时间，且操作简便，值得临床推广应用。 |
| 英文摘要: |
| 【Abstract】 Objective To observe the clinical effect of Moist Exposed Burn Ointment (MEBO) in the treatment of diabetes complicated with II degree scald on foot. Methods Retrospective analysis was made on the medical records of 69 patients with diabetes complicated with II degree scald on foot, admitted to the Department of Burn and Plastic Surgery of Nanhai Hospital Affiliated to Southern Medical University from 2011 to 2017. The 69 patients were divided, based on different treatment methods, into a treatment group - 34 patients who were admitted to the hospital from 2015 to 2017 and treated with MEBO, and a control group - 35 patients who were admitted to the hospital from 2011 to 2014 and treated with recombinant bovine basic fibroblast growth factor (rb-bFGF) gel. The wound healing effect and healing time were compared between the two groups. Results After 21 days of treatment, the effective rate and total effective rate in the treatment group were respectively 76.47% and 94.12%, significantly higher than that of the control group – respectively 28.57% and 68.57%, P<0.01. The wounds in both groups were all healed completely at the end of treatment course. The wound healing time in the treatment group was (25.35±7.41) d and (39.29±10.78) d in the control groups, which showed statistically significant difference, P<0.01. Conclusion MEBO, apart from its easy operation, can promote the wound healing of patients with diabetes complicated with II degree scald and shorten the wound healing time, deserving to be promoted in clinical practice. |
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