| 赵权,田馨如,唐乾利.皮肤再生医疗技术在慢性难愈合创面中的作用机制探讨[J].中国烧伤创疡杂志,2021,(1):11~14. |
| DOI： |
| 中文关键词: 慢性难愈合创面 修复 皮肤再生医疗技术 机制 |
| 英文关键词:Chronic refractory wound Repair MEBT/MEBO Mechanism |
| 基金项目:国家自然科学基金面上项目（81774327） |
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| 摘要点击次数: 1884 |
| 全文下载次数: 4644 |
| 中文摘要: |
| 研究证实，随着人口老龄化的不断加剧，糖尿病性溃疡、压疮等慢性难愈合创面的患病率也逐年上升，且已成为当今世界医学领域迫切解决的难题，因此，探寻能够有效促进创面愈合、缩短慢性难愈合创面患者住院时间的方法意义重大。近年来大量临床研究证实，徐荣祥发明的皮肤再生医疗技术（moist exposed burn therapy/moist exposed burn ointment，MEBT/MEBO）在慢性难愈合创面的修复中取得了显著的临床疗效，为解决慢性难愈合创面的治疗难题做出了巨大贡献。且唐乾利等通过大量基础研究证实，MEBT/MEBO能够通过多种信号通路及多种细胞因子促进慢性难愈合创面的愈合。本研究对MEBT/MEBO的前期研究结果进行总结，以期为MEBT/MEBO治疗慢性难愈合创面的临床应用提供有力理论依据，为进一步深入研究提供新的思路。 |
| 英文摘要: |
| 【Abstract】Studies have confirmed that with the increase of aging population, the incidence of chronic refractory wounds including diabetic ulcers and pressure ulcers is rising year by year, which, nowadays, has become a pressing problem in the medical community across the world. Therefore, it is of great significance to explore effective ways of promoting wound healing and shortening the length of hospital stay for patients with chronic refractory wounds. In recent years, plenty of clinical studies have confirmed that MEBT/MEBO invented by Rongxiang Xu had significant clinical effect in the repair of chronic refractory wounds, contributing a lot to the treatment of such wounds. Moreover, with a large number of basic studies, Tang Qianli, et al have verified that MEBT/MEBO can promote the healing of chronic refractory wounds by regulating some signal pathways and cytokines. This study was to summarize the previous studies on MEBT/MEBO, with the aim of providing theoretical basis for the clinical application of MEBT/MEBO in the treatment of chronic refractory wounds and new insights for further research on this front. |
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