| 魏加国,卢乐磊,于兆海,时秀霞.烧伤创疡再生医疗技术治疗外伤性甲床缺损疗效观察[J].中国烧伤创疡杂志,2021,(1):45~50. |
| DOI： |
| 中文关键词: 烧伤创疡再生医疗技术 湿润烧伤膏 断层甲床自体移植 甲床缺损 外伤 指甲 |
| 英文关键词:Regenerative medical technology for burns, wounds and ulcers (MEBT/MEBO) MEBO Autoplastic transplantation of traumatic nail bed Nail bed defect Trauma Nail |
| 基金项目:山东省中医药科技发展计划项目（2019-1070） |
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| 中文摘要: |
| 目的 探讨烧伤创疡再生医疗技术治疗外伤性甲床缺损的临床效果。方法 选取2016年11月至2019年11月黄岛区人民医院收治的80例外伤性甲床缺损患者作为研究对象，根据治疗方案的不同将其分为再生组40例（46指）与移植组40例（43指），再生组患者行烧伤创疡再生医疗技术治疗，移植组患者行断层甲床自体移植术治疗，对比两组患者伤指疼痛变化情况以及伤指功能和外观恢复情况。结果 治疗4、8、24、48、72 h，再生组患者疼痛评分均明显低于移植组（t=24.660、46.590、33.560、52.600、29.900，P均＜0.001）；治疗3、6、9个月再生组患者伤指功能评分均明显高于移植组（t=16.910、15.540、14.110，P均＜0.001）；治疗9个月，再生组患者缺损甲床及指甲再生效果总优良率为100%，明显优于移植组患者的再生效果总优良率74.42%（Z=-8.391，P＜0.001）。结论 烧伤创疡再生医疗技术治疗外伤性甲床缺损，可有效缓解创面疼痛，促进伤指功能及外观恢复，效果显著。 |
| 英文摘要: |
| 【Abstract】Objective To investigate the clinical effect of the regenerative medical technology for burns, wounds and ulcers (MEBT/MEBO) in the treatment of traumatic nail bed defect. Methods Eighty patients with traumatic nail bed defect, admitted to Huangdao District People’s Hospital from November 2016 to November 2019, were selected as research subjects and divided, based on the different treatments they received, into a regeneration group (40 cases with 46 affected fingers) and a transplantation group (40 cases with 43 affected fingers). The patients in the regeneration group were treated with MEBT/MEBO, whereas the patients in the transplantation group with autoplastic transplantation of nail bed. The changes of pain degree and the recovery of the function and appearance of the injured fingers were compared between the two groups. Results After 4, 8, 24, 48, 72 hours of treatment, the pain scores of the patients in the regeneration group were significantly lower than that in the transplantation group (t=24.660, 46.590, 33.560, 52.600 and 29.900, all P＜0.001); after 3, 6, and 9 months of treatment, the functional scores of the injured fingers in the regeneration group were significantly higher than that in the transplantation group (t=16.910, 15.540 and 14.110, all P<0.001); after 9 months of treatment, the excellent and good rate of the regeneration condition of the defected nail bed and nail in the regeneration group was 100%, which was obviously higher than 74.2% in the transplantation group (Z=-8.391, P<0.001). Conclusion MEBO/MEBT in the treatment of traumatic nail bed defect can significantly relieve wound pain and promote the recovery of function and appearance of the injured fingers. |
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