• 骨质疏松性胸腰椎骨折 PVP 术后邻近椎体再骨折危险因素分析
  • Analysis of Risk Factors of Adjacent Vertebral Refracture after the PVP for Osteoporotic Thoracolumbar Vertebral Fracture
  • 侯立松,王娜娜.骨质疏松性胸腰椎骨折 PVP 术后邻近椎体再骨折危险因素分析[J].中国烧伤创疡杂志,2021,(3):221~224.
    DOI:
    中文关键词:  骨质疏松  胸腰椎骨折  经皮椎体成形术  再发骨折  危险因素
    英文关键词:Osteoporosis  Vertebral fracture  Percutaneous vertebro plasty  Refracture  Risk factor
    基金项目:
    作者单位
    侯立松 中国人民解放军联勤保障部队第九八八医院骨科 
    王娜娜  
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    中文摘要:
          【摘要】 目的 分析骨质疏松性胸腰椎骨折经皮椎体成形术(PVP)术后邻近椎体再骨折的危险因素? 方 法 选取2016年6月至2017年6月中国人民解放军联勤保障部队第九八八医院收治并行PVP治疗的150例骨质 疏松性胸腰椎骨折患者作为研究对象, 收集患者性别?年龄?骨折病史?骨折类型?骨折椎体数量?术前骨密度?术后即刻 Cobb角?骨水泥注射剂量及骨水泥渗漏情况, 根据PVP术后是否发生邻近椎体骨折将患者分为再骨折组和未再骨折组,分析骨质疏松性胸腰椎骨折PVP术后邻近椎体再骨折的相关危险因素? 结果 150 例患者术后出现邻近椎体骨折31例(20.67% ),设为再骨折组; 未出现邻近椎体骨折119例(79.33% ),设为未再骨折组? 单因素分析结果显示, 再骨折组患者中女性?骨折病史及骨水泥渗漏比例明显高于未再骨折组( χ 2 = 3.865? 9.445? 4.186, P = 0.049? P < 0.001? P = 0.041), 年龄明显高于未再骨折组( t = 3.049, P = 0.012), 术前骨密度明显低于未再骨折组( t = 3.402, P = 0.014), 术后即刻 Cobb角明显大于未再骨折组( t = 4.304, P < 0.001), 骨水泥注射剂量明显少于未再骨折组( t = 2.496, P = 0.047); 多因素Logistic 回归分析结果显示, 女性?高龄?骨密度低? Cobb 角过大?骨水泥注射剂量过少及骨水泥渗漏是骨质疏松性胸腰椎骨折PVP术后邻近椎体再骨折的独立危险因素(P 均 < 0.05)? 结论 骨质疏松性胸腰椎骨折PVP术后邻近椎体再骨折与患者性别?年龄?骨密度? Cobb角? 骨水泥注射剂量及骨水泥渗漏情况密切相关?
    英文摘要:
          【Abstract】Objective To analyze the risk factors of adjacent vertebral refracture after the percutaneous vertebro plasty(PVP) for osteoporotic thoracolumbar vertebral fracture. Methods: One hundred and fifty patients who received the PVP operation for osteoporotic thoracolumbar vertebral fracture in Chinese PLA Integrated Logistic Support Force 988th Hospital between June 2016 and June 2017 were selected as research subjects. Data of these subjects were collected including gender, age, fracture history, fracture type, number of fractured vertebra, preoperative bone density, immediate postoperative Cobb angle, injection volume of bone cement and leakage of bone cement. Based on whether there was the occurrence of adjacent vertebral fracture after the PVP operation, the subjects were divided into the refracture group and non-fracture group to analyze the relevant risk factors of adjacent vertebral fracture after the PVP for osteoporotic thoracolumbar vertebral fracture. Results: Among the 150 patients, 31 patients suffered from adjacent vertebral fracture(20.67%) were set as the refracture group, and the other 119 cases without adjacent vertebral fracture(79.33%) were set as the nonfracture group. Single-factor analysis showed that the proportions of female patients, patients with fracture history and patients with leakage of bone cement in the refracture group were obviously higher than that in the nonfracture group(χ2=3.865, 9.445 and 4.186, P=0.049, P<0.001 and P=0.041). Besides, Age of patients was older(t=3.049, P=0.012), bone density was lower(t=3.402, P=0.014), cobb angle was larger(t=4.304, P<0.001) and injection volume of bone cement was less(t=2.496, P=0.047) in the refracture group as compared with that in the nonfracture group. Multivariate Logistic regression analysis found that gender-female, advanced age, low bone density, larger Cobb angle, lower injection volume of bone cement, and leakage of bone cement were the independent risk factors of adjacent vertebral refracture after the PVP for osteoporotic thoracolumbar vertebral fracture(all P < 0.05). Conclusion: The occurrence of adjacent vertebral refracture after the PVP for osteoporotic thoracolumbar vertebral fracture is closely related with patients’ gender, age, bone density, Cobb angle, volume of bone cement and leakage of bone cement.