| 李 嵩,张森林.早期肠内营养治疗大面积重度烧伤患者疗效分析[J].中国烧伤创疡杂志,2021,(6):395~398. |
| DOI： |
| 中文关键词: 大面积重度烧伤 早期 肠内营养 肠外营养 短肽型肠内营养剂 整蛋白型肠内营养剂 |
| 英文关键词:Extensive severe burns Early stage Enteral nutrition Parenteral nutrition Short Peptide Enteral Nutrition Powder High Energy Enteral Nutritional Polymeric Diet |
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| 中文摘要: |
| 【摘要】目的 探讨早期肠内营养治疗对大面积重度烧伤患者的临床疗效。方法 选取2016年1月至2020年1月中国人民解放军联勤保障部队第九九〇医院收治的80例大面积重度烧伤患者作为研究对象，并按照随机数表法将其随机分为观察组与对照组，每组40例，在给予抗感染、抗休克、清创换药等综合治疗的同时，观察组患者入院早期行肠内营养治疗，对照组患者入院早期行肠外营养治疗，对比两组患者血清总蛋白（STP）、白蛋白（ALB）、C反应蛋白（CRP）水平变化情况以及正氮平衡时间、创面愈合时间、创面感染与不良反应发生情况。结果 治疗第7天，观察组患者STP及ALB水平明显高于对照组、CRP水平明显低于对照组（t=3.453、2.354、3.336，P=0.001、0.021、0.001）；观察组患者正氮平衡时间、创面愈合时间均短于对照组（t=6.321、5.056，P均＜0.001）；治疗期间，观察组患者创面感染率与对照组无明显差异（χ2=2.813，P=0.094），而不良反应发生率明显低于对照组（χ2=6.050，P=0.014）。结论 大面积重度烧伤患者早期行肠内营养治疗，可改善患者机体营养状况，促进创面愈合，减少胃肠道不良反应的发生。 |
| 英文摘要: |
| 【Abstract】 Objective To investigate the clinical efficacy of early enteral nutrition therapy in the treatment of extensive severe burns. Methods 80 patients with extensive severe burns， admitted to the 990th Hospital of PLA Joint Logistics Support Force from January 2016 to January 2020， were enrolled and divided into observation group (n = 40) and control group (n = 40) using random number table. In addition to comprehensive treatments such as anti-infection， antishock therapy， debridement and dressing change， upon their admission， patients in observation group were treated with early enteral nutrition therapy whereas control group were treated with early parenteral nutrition therapy. Changes of serum total protein (STP)， albumin (ALB) and C-reactive protein (CRP)， time for positive nitrogen balance， wound healing time， occurrence of wound infection and adverse reactions in the two groups were compared. Results On day 7 of treatment， the levels of STP and ALB in observation group were significantly higher， and the CRP level was significantly lower than control group（t=3.453、2.354、3.336，P=0.001、0.021、0.001）time in observation group were shorter than control group （t=6.321、5.056，P均＜0.001）treatment， no significant difference was observed in terms of wound infection rate between the two groups（χ2=6.050，P=0.014），but adverse reaction rate in observation group was significantly lower than control group (χ2 = 6.050， P =0.014). Conclusion Early enteral nutrition therapy in the treatment of extensive severe burns can improve patients’ nutri-tional status， promote wound healing， and reduce the occurrence of gastrointestinal adverse reactions. |
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