| 胡 伟.北京市某医院门急诊治疗幽门螺杆菌感染性胃溃疡用药分析[J].中国烧伤创疡杂志,2022,(3):221~224. |
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| 中文关键词: 门急诊 幽门螺杆菌感染性胃溃疡 三联疗法 四联疗法 用药分析 |
| 英文关键词:Outpatient and emergency department Helicobacter pylori-infected gastric ulcer Triple therapy Quadruple therapy Analysis of drug use |
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| 中文摘要: |
| 【摘要】 目的 回顾性分析2018—2019年北京市朝阳区双桥医院门急诊幽门螺杆菌 (Hp) 感染性胃溃疡患者用药情况? 方法 从医院合理用药监测系统 (PASS)选取2018年1月至 2019年12月北京市朝阳区双桥医院门急诊收治的1703例Hp感染性胃溃疡患者 (1964份处方) 作为研究对象，查阅患者病历资料，收集并统计患者就诊科室、处方日期、药品名称及数量、用法用量、用药天数等资料，分析用药合理性? 结果 1964 份处方中，不合理处方 56 份(2.85% )，其中消化内科 1865 份处方中，不合理处方25份(1.34% )；综合科 47 份处方中，不合理处方14份(29.79% )；外科门诊27份处方中，不合理处方8份(29.63% )；急诊内科25份处方中，不合理处方9份 (36.00% )? 初次治疗处方 1703 份，不合理处方 17 份 (1.00% )；补救治疗处方 261 份,不合理处方 39 份 (14.94% )? 含铋剂四联方案处方 1956 份，不合理处方 48 份 (2.45% )；三联方案处方 8 份,均为不合理处方? 56份不合理处方中，初次治疗方案不适宜处方15份(26.79% )、补救治疗方案不适宜处方10份(17.86% )、用法用量不适宜处方22份(39.29% )、用药时长不适宜处方9份(16.07% )? 结论 2018—2019 年北京市朝阳区双桥医院门急诊治疗Hp感染性胃溃疡患者用药不合理情况以消化内科以外的其他科室不合理率最高，且多存在于补救治疗中，用法用量、用药时长不适宜情况均有涉及，不合理处方以含左氧氟沙星四联疗法及三联疗法居多? |
| 英文摘要: |
| 【Abstract】 Objective To retrospectively analyze the drug use condition in patients with Helicobacter pylori (Hp)-infected gastric ulcer treated in outpatient and emergency departments of Shuangqiao Hospital from 2018 to 2019. Methods 1703 patients with Hp-infected gastric ulcers (with 1964 prescriptions), admitted to the outpatient and emergency departments of Shuangqiao Hospital of Chaoyang District, Beijing from January 2018 to December 2019, were selected as research subjects. The patient’s medical record data were reviewed to collect such data as visited department, prescription date, drug name and quantity, usage and dosage, duration of drug administration for the analysis of rationality of drug use.Results Among 1964 prescriptions, 56 (2.85% ) were irrational, of which 25 / 1865 (1.34% ) prescriptions from Department of Gastroenterology, 14 / 47 (29.79% ) prescriptions from the General Department, 8 / 27 (29.63% ) prescriptions from Surgery Department, 9 / 25 (36.00% ) prescriptions from Emergency Internal Medicine were irrational.Of the 1964 prescriptions, 1703 prescriptions were made during the initial treatment, in which 17 were irrational (1.00% ); 261 prescriptions were made during the rescue treatment, in which 39 were irrational (14.94% ). Among 1956 prescriptions of bis-Muth-based quadruple therapy, 48 were irrational (2.45%); all 8 prescriptions of triple therapy were irrational.Among the 56 irrational prescriptions, 15 (26.79% ) were unsuitably made for the initial treatment, 10 (17.86%) were unsuitably made for the rescue treatment, 22 (39.29%) were with unsuitable usage and dosage, and 9 (16.07%) had unsuitable duration of drug administration. Conclusion Based on the irrational use of drugs in patients with Hp infected gastric ulcers at the outpatient and emergency departments in Shuangqiao Hospital of Chaoyang District, Beijing, from 2018 to 2019, it is found that the highest rate of irrational drug use was observed in other departments rather than gastroenterology, and most irrational prescriptions were made during the rescue treatment. There were also phenomena of unsuitable usage, dosage and duration of drug administration, and the quadruple therapy and triple therapy containing levofloxacin accounts for the most irrational prescriptions. |
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