| 白 洁,党 明.糖尿病足患者并发肌少症的危险因素分析[J].中国烧伤创疡杂志,2023,35(1):17~20. |
| DOI： |
| 中文关键词: 糖尿病足 肌少症 糖尿病病程 蛋白质摄取量 糖化血红蛋白 Logistic 回归分析 |
| 英文关键词:Diabetic foot Sarcopenia Duration of diabetes Protein intake Glycosylated hemoglobin Logistic regression analysis |
| 基金项目: |
|
| 摘要点击次数: 1711 |
| 全文下载次数: 4393 |
| 中文摘要: |
| 【摘要】 目的 探讨分析糖尿病足患者并发肌少症的相关危险因素。 方法 选取 2019 年 1 月至 2020 年 12 月焦作市人民医院收治的 80 例糖尿病足患者作为研究对象, 收集患者性别、体重指数、糖尿病病程、蛋白质摄 取量、是否合并维生素 D 缺乏症、运动锻炼时间、有无吸烟史、有无饮酒史、是否合并高血压以及糖化血红蛋 白、总胆固醇、甘油三酯、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇水平等资料, 并根据患者是否并发肌少症 将患者分为发生组和未发生组, 多因素 Logistic 回归分析糖尿病足患者并发肌少症的相关危险因素。 结果 80 例 糖尿病足患者中 13 例 (16.25%)患者发生肌少症, 设为发生组; 67 例 (83.75% ) 患者未发生肌少症, 设为未发生组。 单因素分析结果显示, 发生组糖尿病病程≥10 年、蛋白质摄取量不足、合并有维生素 D 缺乏症、运动 锻炼时间 < 30 min / d 的患者比例均明显高于未发生组 ( χ 2 = 5.996?6.701?3.990?10.55,P =0.015?0.010?0.046?0.001)糖化血红蛋白水平亦明显高于未发生组 ( t=3.189,P =0.002); 多因素 Logistic 回归分析结果显示, 糖尿病病程≥10 年、蛋白质摄取量不足、合并有维生素 D 缺乏症、运动锻炼时间 < 30 min / d、糖化血红蛋白水平高是糖尿病足患者并发肌少症的独立危险因素 (95% CI 为 1.259 ～15.067、1.369 ～20.962、1.117 ～19.997、1.822 ～43.833、1.474 ～1.996, P = 0.020、0.016、0.035?0.007?0.000)。结论 糖尿病足患者肌少症发生情况与糖尿病病程、蛋白质摄取量、维生素 D 缺乏症、运动锻炼时间及糖化血红蛋白水平密切相关。 |
| 英文摘要: |
| 【Abstract】 Objective To study the related risk factors for sarcopenia in patients with diabetic foot. Methods 80 patients diabetic foot, admitted to Jiaozuo People’s Hospital from January 2019 to December 2020, were enrolled as research subjects, and their data were collected including sex, body mass index, duration of diabetes, protein intake, complicated with vitamin D deficiency or not, exercise time, smoking history, drinking history, complicated with hypertension or not, and levels of glycosylated hemoglobin (GHb), total cholesterol, triglyceride, low density lipoprotein cholesterol and high density lipoprotein cholesterol. The subjects were divided into occurrence group and non-occurrence group based on whether they were complicated with sarcopenia. Multivariate Logistic regression analysis was used to analyze related risk factors for sarcopenia in patients with diabetic foot. Results Of the 80 patients with diabetic foot, 13 (16.25%) developed sarcopenia, being set as the occurrence group, the other 67 (83.75%) who did not suffer sarcopenia were set asnon-occurrence group. The results of univariate analysis showed that the proportions of patients with more than 10 years of duration of diabetes, insufficient protein intake, vitamin D deficiency, and exercise time < 30 min/ d in the occurrence group were significantly higher compared with the non-occurrence group (χ 2 = 5.996, 6.701, 3.990 and 10.533, P =0.015, 0.010, 0.046 and 0.001), the level of glycosylated hemoglobin was also significantly higher than the non-occurrence group (t =3.189, P =0.002); multivariate Logistic regression analysis showed that duration of diabetes ≥10 years, insufficient protein intake, vitamin D deficiency, and exercise time <30 min/ d, and high level of glycosylated hemoglobin were independent risk factors of sarcopenia in patients with diabetic foot (95%CI: 1.259 -15.067, 1.369 -20.962, 1.117-19.997, 1.822 -43.833, and 1.474 -1.996, P =0.020, 0.016, 0.035, 0.007 and 0.000). Conclusion The occurrence of sarcopenia in patients with diabetic foot is closely associated with the duration of diabetes, protein intake, vitamin D deficiency, exercise time and the level of glycosylated hemoglobin. |
|
|
|
|
