| 来庆东,金晓明,李 鹏,吕志远.富血小板血浆治疗慢性难愈合创面疗效分析[J].中国烧伤创疡杂志,2023,35(1):26~28. |
| DOI： |
| 中文关键词: 慢性难愈合创面 富血小板血浆 创面 自体皮移植 糖尿病足 下肢动脉性溃疡 放射性溃疡 压疮 |
| 英文关键词:Chronic refractory wound Platelet-rich plasma Wound Autologous skin graft Diabetic foot Arterial ulcer of lower extremity Radiation-induced ulcer Pressure ulcer |
| 基金项目: |
|
| 摘要点击次数: 1929 |
| 全文下载次数: 4698 |
| 中文摘要: |
| 【摘要】目的探讨富血小板血浆(PRP)治疗慢性难愈合创面的临床疗效。方法给予2019年6月至2021年5月淄博岜山万杰医院收治的30例慢性难愈合创面患者行PRP治疗,待肉芽组织完全覆盖创面后对合并肌腱或骨外露的创面行自体皮移植封闭,其他创面全程应用PRP换药治疗,观察创面愈合情况。结果30例患者创面均完全愈合,其中14例患者于PRP治疗18～32d后肉芽组织完全覆盖创面,行自体皮移植治疗后创面愈合;其余16例患者于PRP治疗16～40d后创面愈合,愈合时间为(26.7±7.0)d。治疗期间,所有患者均未出现过敏、排异、感染、局部组织异常增生及创面恶化等情况。结论PRP可有效促进慢性难愈合创面愈合,疗效显著,且改良后的PRP制备过程简便易行,费用低廉,安全性较高,值得基层医院推广应用。 |
| 英文摘要: |
| 【Abstract】 Objective To study the therapeutic effect of platelet?rich plasma ( PRP) on chronic refractory wounds. Methods 30 patients with chronic refractory wounds, admitted to Zibo Bashan Wanjie Hospital from June 2019 to May 2021, were treated with PRP. Autologous skin graft was performed on the wounds complicated with tendon or bone exposure when the wounds were covered entirely by granulation tissues, while for the other wounds, the dressing change of PRP were performed throughout the whole course of treatment, and the wound healing condition was observed. Results The wounds of all the 30 patients were healed completely. The wounds of 14 patients were completely covered with granulation tissues after 18 -32 days of PRP treatment, and then healed after autologous skin graft; the wounds of the other 16 patients were healed after 16 -40 days of PRP treatment, and the healing time was (26. 7 ±7. 0) days. During the course of treatment, none of the patients suffered from allergies, rejection reaction, infection, hyperplasia of local tissues or wound deterioration. Conclusion PRP can effectively promote the healing of chronic refractory wounds, and realize definite therapeutic effect. Moreover, the modified PRP is easy to prepare, inexpensive in price, and much safe to use, deserving to be promoted in grassroots hospitals. |
|
|
|
|
