• 经皮椎体成形术治疗骨质疏松性椎体压缩性骨折疗效分析
  • Therapeutic Effect of Percutaneous Vertebroplasty in the Treatment of Osteoporotic Vertebral Compression Fracture
  • 韩耀辉,赵 斌.经皮椎体成形术治疗骨质疏松性椎体压缩性骨折疗效分析[J].中国烧伤创疡杂志,2023,35(1):46~49.
    DOI:
    中文关键词:  经皮椎体成形术  骨质疏松性椎体压缩性骨折  骨质疏松  椎体骨折  椎体功能
    英文关键词:Percutaneous vertebroplasty  Osteoporotic vertebral compression fracture  Osteoporosis  Vertebral fracture  Vertebral function
    基金项目:
    作者单位
    韩耀辉 225400 江苏 泰兴, 泰兴市中医院骨科 
    赵 斌  
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    中文摘要:
          【摘要】 目的 探究经皮椎体成形术 (PVP) 治疗骨质疏松性椎体压缩性骨折 (OVCF) 的临床疗效。方法 选取 2019 年 12 月至 2020 年 11 月泰兴市中医院收治的 154 例 OVCF 患者作为研究对象, 并按照随机数表法将其随机分为观察组 (77 例) 与对照组 (77 例), 观察组患者采用 PVP 治疗, 对照组患者采用过伸复位治疗,对比观察两组患者疼痛程度、椎体功能、伤椎前缘高度、Cobb 角以及并发症发生情况。结果 术后 1 周及术后1、5 个月, 观察组患者视觉模拟评分法 (VAS) 评分及 Oswestry 功能障碍指数 (ODI) 评分均明显低于对照组(VAS: t = 1. 985、2. 733、2. 490, P = 0. 049、0. 007、0. 014; ODI: t = 2. 726、8. 181、8. 497, P = 0. 007、P <0. 001、P <0. 001); 术后 1 个月, 观察组患者伤椎前缘高度明显高于对照组 (t =6. 786, P <0. 001), Cobb 角明显小于对照组 (t =20. 927, P <0. 001); 观察组患者术后并发症发生率为 5. 19%, 明显低于对照组患者的术后并发症发生率 15. 58% (χ 2 =4. 464, P =0. 035)。结论 PVP 可明显缓解 OVCF 患者疼痛程度, 改善患者椎体功能,且安全性较高。
    英文摘要:
          【Abstract】 Objective To study the therapeutic effect of percutaneous vertebroplasty (PVP) in the treatment of osteoporotic vertebral compression fracture (OVCF). Methods 154 patients with OVCF, admitted to Taixing Hospital of TCM from December 2019 to November 2020, were enrolled as research subjects and then divided, using the random number table, into observation group (n = 77) and control group (n = 77). Patients in observation group were treated with PVP, whereas the patients in control group were treated with hyperextension reduction. The pain degree, vertebral function,anterior edge height and Cobb angle of injured vertebra, and occurrence of complications were compared between the two groups. Results The scores of visual analogue scale (VAS) and Oswestry disability index (ODI) of patients were significantly lower in observation group compared with control group respectively on one week, one month and five months after operation (VAS: t =1.985, 2.733 and 2.490, P = 0.049, 0.007 and 0.014; ODI: t = 2.726, 8.181 and 8.497, P =0.007, P <0.001, P < 0.001); one month after operation, in observation group, the height of the anterior edge of the injured vertebra was significantly higher (t = 6.786, P < 0.001), and the Cobb angle was significantly smaller (t =20.927, P <0.001), compared with control group; the incidence of postoperative complications was 5.19% in observation group, significantly lower than 15.58% in control group (χ 2 = 4.464, P = 0.035). Conclusion PVP can significantly alleviate the pain of patients with OVCF, improve their vertebral function, and is also very safe to use.