• 术前血清白蛋白水平对老年股骨颈骨折髋关节置换术后切口感染的预测价值分析
  • Value Analysis of Preoperative Serum Albumin Level in Predicting Incision Infection after Hip Replacement for Femoral Neck Fracture in the Elderly
  • 李东艳,王久清.术前血清白蛋白水平对老年股骨颈骨折髋关节置换术后切口感染的预测价值分析[J].中国烧伤创疡杂志,2023,(3):208~211.
    DOI:
    中文关键词:  股骨颈骨折  髋关节置换术  白蛋白  术后感染  切口感染
    英文关键词:Femoral neck fracture  Hip replacement  Albumin  Postoperative infection  Incision infection
    基金项目:河南省医学科技攻关计划项目 (LHGJ20190518)
    作者单位
    李东艳 475000 河南 开封, 河南大学第一附属医院急诊创伤外科 
    王久清  
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    中文摘要:
          【摘要】 目的 探讨术前血清白蛋白水平对老年股骨颈骨折患者髋关节置换术后切口感染的预测价值。方法 选取 2021 年 6 月至 2022 年 6 月河南大学第一附属医院收治的 96 例行人工髋关节置换术治疗的老年股骨颈骨折患者作为研究对象, 收集患者性别、年龄、麻醉方式、手术方式、是否合并糖尿病、是否合并高血压、是否长期使用抗凝药物、术前血清白蛋白水平等资料, 根据髋关节置换术后 1 周切口是否发生感染将患者分为感染组与未感染组, 分析术前血清白蛋白水平对老年股骨颈骨折髋关节置换术后切口感染的预测价值。结果 96 例老年股骨颈骨折患者髋关节置换术后 1 周发生切口感染 7 例 ( 7.29% ), 设为感染组; 未发生切口感染 89 例(92.71% ), 设为未感染组。 点二列相关性分析结果显示, 术前血清白蛋白水平与老年股骨颈骨折髋关节置换术后切口感染呈显著负相关性 (r = - 0.247, P = 0.015); 受试者工作特征 (ROC) 曲线分析结果显示, 术前血清白蛋白水平预测老年股骨颈骨折髋关节置换术后切口感染的曲线下面积 (AUC) 为 0.773, 特异度为 71.4% , 敏感度为 75.3%。结论 术前血清白蛋白水平可作为临床预测老年股骨颈骨折患者髋关节置换术后切口感染的生物学指标。
    英文摘要:
          【Abstract】 Objective To analyze the predictive value of preoperative serum albumin level for incision infection after hip replacement for femoral neck fracture in the elderly. Methods 96 elderly patients with femoral neck fracture, who underwent artificial hip replacement in The First Affiliated Hospital of Henan University between June 2021 and June 2022 were enrolled as research subjects, and the data of patients were collected, including sex, age, anesthesia method, surgical method, whether complicated with diabetes and hypertension or not, whether administered anticoagulant drugs for a long time, and serum albumin level before surgery. The patients were divided into infection group and non-infection group based on whether incision infection occurred one week after hip replacement to analyze the value of preoperative serum albumin level in predicting incision infection after hip replacement for femoral neck fracture in the elderly. Results One week afterhip replacement, among the 96 elderly patients with femoral neck fracture, 7 cases (7.29% ) developed incision infection,being set as infection group, and the other 89 cases (92.71% ) without incision infection were set as non-infection group. The point biserial correlation analysis showed that the preoperative level of serum albumin had a strong negative association with the occurrence of incision infection of elderly patients with femoral neck fracture after hip replacement ( r = - 0.247,P = 0.015). The receiver operating characteristic (ROC) curve showed that the area under the curve (AUC) of preopera-tive serum albumin level in predicting incision infection of the elderly patients with femoral neck fracture after hip replacement was 0.773, with the specificity being 71.4% and the sensitivity being 75.3% . Conclusion The preoperative serum albumin level can be used as a biological indicator in clinical practice to predict the occurrence of incision infection in elderly patients with femoral neck fracture after hip replacement.