| 孙 磊,段晓敏.桃红补骨汤在骨质疏松性股骨转子间骨折术后的应用效果分析[J].中国烧伤创疡杂志,2023,(4):310~313. |
| DOI： |
| 中文关键词: 桃红补骨汤 骨质疏松 股骨转子间骨折 髓内钉 骨折愈合 髋关节功能 |
| 英文关键词:Taohong Bugu Decoction Osteoporosis Femoral intertrochanteric fracture Intramedullary nail Fracture healing Hip joint function |
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| 中文摘要: |
| 【摘要】 目的 探讨桃红补骨汤在骨质疏松性股骨转子间骨折 (FIF) 防旋型股骨近端髓内钉内固定术后的应用效果。方法 选取 2020 年 3 月至 2022 年 3 月许昌北海医院收治的 80 例骨质疏松性 FIF 患者作为研究对象, 按照随机数表法将其随机分为研究组 (40 例) 与对照组 (40 例), 研究组患者于防旋型股骨近端髓内钉内固定术后口服碳酸钙 D 3 片和桃红补骨汤, 对照组患者于防旋型股骨近端髓内钉内固定术后单纯口服碳酸钙 D 3片, 对比观察两组患者术后下床活动时间、骨折愈合时间以及骨代谢水平、疼痛程度、髋关节功能恢复情况与并发症发生情况。结果 研究组患者术后下床活动时间与骨折愈合时间均明显短于对照组 (t = 7.390、4.564, P均 <0.001)。治疗 4 周后, 研究组患者血清骨钙蛋白 (BGP)、骨碱性磷酸酶 (BALP) 水平以及 Harris 评分均明显高于对照组 (t =7.467、14.401、7.504, P 均 <0.001); 血清 I 型胶原羧基端肽 β 特殊序列 (β-CTX) 水平以及视觉模拟评分法 (VAS) 评分均明显低于对照组 (t =5.005、6.437, P 均 <0.001)。 治疗期间, 研究组患者并发症发生率为5.00%, 明显低于对照组患者的并发症发生率 22.50% (χ 2 =5.165, P =0.023)。结论 桃红补骨汤可明显促进骨质疏松性 FIF 防旋型股骨近端髓内钉内固定术后骨折愈合, 减轻患者疼痛程度, 改善患者髋关节功能。 |
| 英文摘要: |
| 【Abstract】 Objective To study the effect of applying Taohong Bugu Decoction after the proximal femoral nailantirotation (PFNA) procedure for the osteoporotic femoral intertrochanteric fracture (FIF). Methods 80 patients withosteoporotic FIF admitted into Xuchang Beihai Hospital between March 2020 and March 2022 were enrolled as researchsubjects, and then divided into study group (n = 40) and control group (n = 40) using the random number table. Patients in the study group were treated with oral administration of Calcium Carbonate and Vitamin D3 Tablets and Taohong BuguDecoction after the PFNA, while patients in the control group were treated with oral administration of Calcium Carbonate and Vitamin D3 Tablets alone after the PFNA. The time to first ambulation after operation, fracture healing time, level of bonemetabolism, pain degree, recovery condition of hip joint functions, and occurrence of complications of patients were compared between the two groups. Results The time to first ambulation after operation and fracture healing time of patients were obviously shorter in the study group compared with the control group (t = 7. 390 and 4. 564, both P < 0. 001). After 4weeks of treatment, the levels of serum bone gammacarboxy glutamic acidcontaining protein (BGP, also called osteocalcin) and bone alkaline phosphatase (BALP), and Harris scores of patients in the study group were all markedly higher than that in the control group (t = 7. 467, 14. 401 and 7. 504, all P < 0. 001), and the level of β cross-linked C-telopeptides of type I collagen (β-CTX) and the visual analogue scale (VAS) score of patients were markedly lower in the study group ( t = 5. 005 and 6. 437, both P < 0. 001). During the course of treatment, the incidence of complications in the study group was 5. 00% , being obviously lower than the corresponding 22. 50% in the control group (χ2= 5. 165, P = 0. 023 ).Conclusion Taohong Bugu Decoction can effectively promote the fracture healing of patients with osteoporotic femoral intertrochanteric fracture after the PFNA, alleviate patients’ pain and improve their hip joint functions. |
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