| 刘恒鑫,陈海龙,马俊杰.血栓风险分级干预在膝关节置换患者围手术期的应用效果分析[J].中国烧伤创疡杂志,2023,(5):396~400. |
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| 中文关键词: 血栓 膝关节置换 凝血功能 血流速度 静脉血栓栓塞 深静脉血栓形成 |
| 英文关键词:Thrombosis Knee replacement Coagulation function Velocity of blood flow Venous thromboembolism Deep vein thrombosis |
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| 中文摘要: |
| 【摘要】 目的 探讨血栓风险分级干预在膝关节置换患者围手术期的应用效果。方法 选取 2020 年 12 月至 2022 年 11 月社旗县人民医院收治的拟行膝关节置换术治疗的65例膝关节疾病患者作为研究对象, 根据不同干预方法将其分为分级干预组(32例)与常规干预组(33例), 分级干预组患者于膝关节置换围手术期采用血栓风险分级干预, 常规干预组患者于膝关节置换围手术期采用常规干预, 对比观察两组患者凝血功能、下肢静脉血流速度及深静脉血栓发生情况。结果 术后第 2 天, 分级干预组患者凝血酶原时间 (PT)、活化部分凝血活酶时间(APTT)均明显长于常规干预组( t = 40.380、10.443, P均< 0.001),纤维蛋白原 (FIB)水平明显低于常规干预组 (t = 12.961, P < 0.001),髂静脉、股总静脉、腘静脉血液流速均明显快于常规干预组 ( t = 8.480、9.074、12.386, P均< 0.001); 术后随访2个月, 分级干预组患者深静脉血栓发生率明显低于常规干预组(χ2=6.410, P = 0.011)。结论 血栓风险分级干预能有效改善膝关节置换患者术后凝血功能, 提高血流速度, 预防深静脉血栓形成。 |
| 英文摘要: |
| 【Abstract】 Objective To study the effect of graded intervention of thrombosis risks during the perioperative period of knee replacement. Methods 65 patients with knee disorders admitted into Sheqi People’ s Hospital between December 2020 and November 2022 for knee replacement were enrolled as research subjects, and divided into graded intervention group (n = 32) and routine intervention group ( n = 33) based on different intervention methods they received. Patients in the graded intervention group were given the graded intervention of thrombosis risks during the perioperative period of knee replacement, while patients were given the routine intervention of thrombosis risks during the perioperative period of knee replacement in the routine intervention group. The coagulation function, blood flow velocity of lower extremity veins and the occurrence of deep vein thrombosis of patients were compared between the two groups. Results On day 2after surgery, the prothrombin time (PT) and activated partial thromboplastin time (APTT) of patients in the graded intervention group were obviously longer than that in the routine intervention group (t = 40.380 and 10.443, both P < 0.001), the level of fibrinogen (FIB) was markedly lower (t = 12.961, P < 0.001) and the blood flow velocities of iliac vein, common femoral vein and popliteal vein were significantly faster in the graded intervention group compared with the routine intervention group (t = 8.480, 9.074 and 12.386, all P < 0.001). During the follow-up two months after surgery, the incidence of deep vein thrombosis in the graded intervention group was obviously lower than that in the routine intervention group( χ2= 6.410, P = 0.011). Conclusion The graded intervention of thrombosis risks can effectively improve the coagulation function of patients after knee replacement, accelerate the blood flow velocity and prevent the occurrence of deep vein thrombosis. |
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