| 王一枝,张 淼,杨璐珊,赵 霞,陈蹬蹬,郭 杏.烧伤患者并发深静脉血栓危险因素的Meta分析[J].中国烧伤创疡杂志,2023,(6):443~451. |
| DOI： |
| 中文关键词: 烧伤 深静脉血栓 危险因素 系统评价 Meta 分析 |
| 英文关键词:Burns Deep vein thrombosis Risk factors Systematic evaluation Meta-analysis |
| 基金项目:四川省教育厅项目 (18ZB0639) |
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| 中文摘要: |
| 【摘要】 目的 系统分析烧伤患者并发深静脉血栓的危险因素。方法 检索 PubMed、Embase、The Cochrane Library、Web of Science、中国生物医学文献数据库、中国期刊全文数据库 (中国知网)、中国学术期刊数据库 (万方)、中文科技期刊数据库 (维普) 等数据库建库至 2021 年 9 月公开发表的烧伤患者并发深静脉血栓危险因素的相关中英文文献, 筛选并提取相关资料, 采用纽卡斯尔-渥太华量表 (NOS) 进行质量评价, 采用RevMan 5.4 软件进行 Meta 分析? 结果 检索后通过筛选共获得文献 15 篇, 总样本量 103976 例, 确诊深静脉血栓 852 例, 共纳入危险因素 18 个, NOS 评分均 > 5 分, 故全部纳入 Meta 分析。结果显示, 年龄、肥胖、烧伤面积≥10% TBSA、吸入性损伤、下肢烧伤、躯干烧伤、热力烧伤、电烧伤、排除血栓后输血、中心静脉置管、股静脉置管、创面感染、卧床时间≥20 d、植皮是烧伤患者并发深静脉血栓的危险因素 (OR = 1.01、2.04、31.65?2.90、8.38、7.78、0.11、6.61、10.58、3.02、59.83、3.08、28.21、2.83, 95% CI 为 1.01 ~ 1.02、1.45 ~2.88、8.69 ~ 115.20、2.22 ~ 3.79、4.43 ~ 15.86、4.16 ~ 14.55、0.06 ~ 0.22、3.04 ~ 14.38、5.27 ~ 21.23?2.29 ~ 3.98、19.16 ~ 186.80、1.68 ~ 5.66、7.97 ~ 99.82、1.58 ~ 5.07)。结论 烧伤患者并发深静脉血栓的危险因素涉及患者年龄、体重指数、烧伤面积、烧伤部位、致伤原因、治疗方法等多个方面。 |
| 英文摘要: |
| 【Abstract】 Objective To systematically analyze the risk factors of deep vein thrombosis in burn patients.Methods Chinese and English literature search was conducted to retrieve studies on the risk factors of deep vein thrombosis in burn patients published by September 2021 from the establishment of the following databases including PubMed, Embase, The Cochrane Library, Web of Science, Chinese Biomedical Literature Database, China National Knowledge Infrastructure (CNKI), China Science Periodical Database (Wanfang), and China Science and Technology Journal Database (VIP), and the qualified study documents were screened out and extracted from the retrieved literature. The Newcastle-Ottawa scale (NOS) was used to evaluate the quality, and RevMan 5.4 software was applied for Meta-analysis. Results A total of 15 papers were screened out from the retrieved literature, involving a total sample of 103976, of whom 852 patients were diagnosed with deep vein thrombosis, with a total of 18 risk factors involved. The 15 papers all scored > 5 points by NOS, and thus were all included in the Meta-analysis. The results showed that age, obesity, burn area ≥ 10% TBSA, inhalation injury, lower extremity burn, trunk burn, thermal burn, electric burn, blood transfusion after exclusion of thrombus, central vein catheter, femoral vein catheter, wound infection, bedridden time ≥ 20 days, skin grafting were risk factors for deep vein thrombosis in burn patients (OR = 1.01, 2.04, 31.65, 2.90, 8.38, 7.78, 0.11, 6.61, 10.58, 3.02, 59.83, 3.08, 28.21 and 2.83, 95% CI: 1.01 - 1.02, 1.45 - 2.88, 8.69 - 115.20, 2.22 - 3.79, 4.43 - 15.86, 4.16 - 14.55, 0.06 - 0.22, 3.04 - 14.38, 5.27 - 21.23, 2.29 - 3.98, 19.16 - 186.80, 1.68 - 5.66, 7.97 - 99.82, 1.58 - 5.07). Conclusion The risk factors of deep vein thrombosis in burn patients may involve many aspects of patients including their age, body mass index, burn area, burn location, cause of injury, and treatment methods, etc. |
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