| 甘 霖,李 密.儿童消化性溃疡临床特征及危险因素分析[J].中国烧伤创疡杂志,2024,(1):58~61. |
| DOI： |
| 中文关键词: 儿童 消化性溃疡 十二指肠溃疡 复合性溃疡 胃溃疡 临床特征 危险因素 Logistic 回归分析 |
| 英文关键词:Children Peptic ulcer Duodenal ulcer Compound ulcer Gastric ulcer Clinical features Risk
factors Logistic regression analysis |
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| 摘要点击次数: 1261 |
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| 中文摘要: |
| 【摘要】 目的 分析儿童消化性溃疡的临床特征及相关危险因素。方法 选取 2020 年 3 月至 2023 年 3 月南阳医学高等专科学校第一附属医院收治的 260 例消化性溃疡患儿 (设为溃疡组), 以及 260 名健康儿童 (设为健康组) 作为研究对象, 收集研究对象性别、年龄、家族史、饮食喜好以及患儿临床症状 (呕吐、恶心、反酸?嗳气等) 及体征 (上腹压痛等) 等情况, 分析儿童消化性溃疡的临床特征, 并采用多因素 Logistic 回归分析儿童消化性溃疡的相关危险因素。结果 儿童消化性溃疡患儿中男性 (84.23%) 多于女性 (15.77%), 年龄以学龄期儿童 ( 46.92%) 和 青 春 期 儿 童 ( 40.77%) 为 主, 溃 疡 类 型 以 十 二 指 肠 溃 疡 ( 71.15%) 和 单 发 溃 疡(72.69%) 为主, 主要临床表现为腹痛 (71.15%)、呕吐 (63.08%) 和黑便 (48.85%), 且腹痛部位主要为剑突下、脐周和上腹部, 其中仅 22.12%表现为与进食相关。多因素 Logistic 回归分析结果显示, 有家族史、喜好冷食、喜好酸辣、经常吃外卖、幽门螺杆菌感染、心理障碍、家庭不和睦、住校/小餐桌是儿童消化性溃疡的独立危险因素 (95% CI 为 1.848 ~ 32.710、1.040 ~ 3.659、1.334 ~ 11.937、1.182 ~ 11.257、1.499 ~ 9.424、1.935 ~20.817、1.188 ~ 6.046、1.178 ~ 4.867, P = 0.005、0.037、0.013、0.024、0.004、0.002、0.017、0.015)。结论 儿童消化性溃疡以学龄期和青春期男性儿童为主, 溃疡类型主要为十二指肠溃疡, 临床表现主要为腹痛、呕吐和黑便; 有家族史、喜好冷食、喜好酸辣、经常吃外卖、幽门螺杆菌感染、心理障碍、家庭不和睦、住校/小餐桌是儿童消化性溃疡的独立危险因素。 |
| 英文摘要: |
| 【Abstract】 Objective To analyze the clinical features and risk factors for peptic ulcers in children. Methods 260 children with peptic ulcers, admitted to The First Affiliated Hospital of Nanyang Medical College between March 2020 and March 2023, were selected as research subjects, being set as the ulcer group. Meanwhile, 260 healthy children were chosen to be set as the healthy group. Data of these research subjects, including sex, age, family history, dietary preferences, clinical symptoms (vomiting, nausea, acid reflux, belching, etc. ), and physical signs ( upper abdominal tenderness, etc. ), were collected to analyze the clinical features of children with peptic ulcer, and multivariate Logistic regression analysis was conducted to analyze the risk factors for peptic ulcer in children. Results There were more males (84. 23%) than females ( 15. 77%) in children with peptic ulcer, mainly school-age children ( 46. 92%) and adolescent children(40. 77%). Duodenal ulcers ( 71. 15%) and single ulcers ( 72. 69%) were the main types of ulcers. The main clinical features of peptic ulcers were abdominal pain ( 71. 15%), vomiting ( 63. 08%), and black stool ( 48. 85%), and the abdominal pain mainly located in subxiphoid, peri-umbilicus, and upper abdomen, of which only 22. 12% was in relation to food intake. The results of multivariate Logistic regression analysis showed that family history, cold food preference, hot and sour taste preference, frequent takeaways diet, Helicobacter pylori infection, psychological disorder, family disharmony, and boarding in at the school or dining at small dining tables were the independent risk factors for pediatric peptic ulcer (95%CI: 1. 848 - 32. 710, 1. 040 - 3. 659, 1. 334 - 11. 937, 1. 182 - 11. 257, 1. 499 - 9. 424, 1. 935 - 20. 817, 1. 188 - 6. 046 and 1. 178-4. 867, P= 0. 005, 0. 037, 0. 013, 0. 024, 0. 004, 0. 002, 0. 017 and 0. 015). Conclusion Pediatric peptic ulcers were predominantly found in school-age and adolescent male children, with duodenal ulcer as the commonly-seen type, and abdominal pain, vomiting, and black stool as the main clinical features. Family history, cold food preference, hot and sour taste preference, frequent takeaways diet, Helicobacter pylori infection, psychological disorders, family disharmony, and boarding in at the school or dining at small dining tables were independent risk factors for peptic ulcer in children. |
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