| 王巧格,傅伊菲.医用臭氧联合水胶体敷料在ICU患者压疮治疗中的应用效果分析[J].中国烧伤创疡杂志,2024,(2):101~104. |
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| 中文关键词: 水胶体敷料 医用臭氧 压疮 重症监护室 渗液量 疼痛 炎症反应 感染 |
| 英文关键词:Hydrocolloid dressing Medical ozone Pressure ulcer ICU Exudate volume Pain Inflammatory response Infection |
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| 中文摘要: |
| 【摘要】 目的 探讨医用臭氧联合水胶体敷料在重症监护室 (ICU) 患者压疮治疗中的应用效果。 方法 选取 2020 年 6 月至 2021 年 6 月河南科技大学第一附属医院收治的 60 例并发压疮的 ICU 患者作为研究对象, 按照不同治疗方法将其分为观察组 (30 例) 和对照组 (30 例), 观察组患者压疮创面采用医用臭氧联合水胶体敷料治疗, 对照组患者压疮创面单纯采用水胶体敷料治疗, 对比观察两组患者创面面积、渗液量、疼痛程度与血清炎症指标水平、创面病原菌检出率及临床疗效。 结果 治疗 14 d 后, 观察组患者创面渗液量明显少于对照组 ( t =2.134, P= 0.037), 视觉模拟评分法 (VAS) 评分及血清肿瘤坏死因子-α (TNF-α)、白细胞介素-6 ( IL-6) 水平均明显低于对照组 ( t = 3.504、3.665、3.685, P 均< 0.001), 而创面面积及白细胞计数与对照组无明显差异(t = 1.113、0.714, P= 0.270、0.478)。 治疗 28 d 后, 观察组患者创面均未检出病原菌, 明显低于对照组患者的创面病原菌检出率 26.67% (χ2 = 9.231, P= 0.002)。 治疗 28 d 后, 观察组患者治疗总有效率为 96.67%, 明显高于对照组患者的治疗总有效率 76.67% (χ2 = 5.192, P = 0.023)。 结论 医用臭氧联合水胶体敷料治疗 ICU 患者压疮创面, 可有效减少创面渗液量, 缓解创面疼痛, 降低机体炎症反应程度, 抑制创面病原菌定植, 提高治疗效果。 |
| 英文摘要: |
| 【Abstract】 Objective To study the clinical efficacy of medical ozone combined with hydrocolloid dressing in the treatment of pressure ulcer in ICU patients. Methods 60 ICU patients with pressure ulcer, admitted to The First Affiliated Hospital of Henan University of Science and Technology from June 2020 to June 2021, were enrolled as research subjects and divided into study group ( n = 30) and control group ( n = 30) based on the different treatments they received. The wounds in the study group were treated with medical ozone combined with hydrocolloid dressing, while the wounds in the control group were treated with hydrocolloid dressing alone. The following indicators including wound area, exudate volume, pain degree, levels of serum inflammatory factors, detection rates of wound pathogen and clinical efficacy were compared between the two groups. Results After 14 days of treatment, the volume of wound exudate in the study group was significantly less than that in the control group (t = 2.134, P= 0.037), the visual analogue scale (VAS) and the levels of serum tumor necrosis factor-α (TNF-α) and interleukin-6 ( IL-6) were significantly lower than those in the control group ( t = 3.504, 3.665 and 3.685, all P<0.001), but there were no statistically significant differences between the two groups in terms of the wound area and white blood cell count ( t = 1.113 and 0.714, P = 0.270 and 0.478). After 28 days of treatment, no pathogen was detected on the wounds of patients in the study group, which was significantly lower than the 26.67% detection rate of pathogen in the control group ( χ2 = 9.231, P = 0.002), and the total effective rate in the study group was 96.67%, significantly higher than the corresponding 76.67% in the control group (χ2 = 5.192, P= 0.023). Conclusion The combined application of medical ozone and hydrocolloid dressing in the treatment of pressure ulcer in ICU patients can effectively reduce the wound exudate volume, relieve wound pain, decrease the degree of inflammatory reaction, inhibit pathogen colonization in wounds, and improve treatment effect. |
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