| 彭清生,付 芬,周冬龙.蓝光照射治疗蝮蛇咬伤效果分析[J].中国烧伤创疡杂志,2024,(3):201~204. |
| DOI： |
| 中文关键词: 蓝光照射 蝮蛇咬伤 肿胀 疼痛 炎症反应 等效性试验 |
| 英文关键词:Blue-light irradiation Viper bites Swelling Pain Inflammatory reaction Equivalence trial |
| 基金项目:江西省卫生健康委科技计划项目(SKJP220211610) |
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| 中文摘要: |
| 【摘要】 目的 分析探讨蓝光照射治疗蝮蛇咬伤的临床效果。 方法 选取 2022 年 3 月至 2023 年 5 月宜春市中医院收治的 80 例蝮蛇咬伤患者作为研究对象, 按照不同治疗方法将其分为观察组 (40 例) 和对照组 (40例), 观察组患者在预防破伤风、中和蛇毒、中药糊剂外敷等治疗的基础上加用蓝光照射治疗, 对照组患者在预防破伤风、中和蛇毒、中药糊剂外敷等治疗的基础上加用头孢唑林钠治疗, 对比观察两组患者住院时间、患肢肿胀及疼痛程度、炎症因子水平与临床疗效。 结果 观察组患者住院时间与对照组无明显差异 ( t = 1.858, P =0.067)。 治疗第 3、6 天, 观察组患者患肢肿胀、疼痛评分及治疗第 6 天白细胞计数 ( WBC)、C 反应蛋白(CRP) 水平与对照组均无明显差异 (治疗第 3 天: t = 1.670、1.868, P = 0.099、0.066; 治疗第 6 天: t / Z =-1.835、1.932、1.783、0.924, P= 0.070、0.057、0.077、0.358)。 治疗 7 d 后, 观察组患者中治愈 30 例、显效9 例、有效 1 例, 与对照组患者的治愈 32 例、显效 6 例、有效 2 例无明显差异 (Z= -0.450, P= 0.653)。 结论 蓝光照射能够改善蝮蛇咬伤后肢体肿胀和疼痛症状, 减轻全身炎症反应, 治疗效果与头孢唑林钠相当, 可替代治疗蝮蛇咬伤的抗生素类药物。 |
| 英文摘要: |
| 【Abstract】 Objective To analyze the clinical efficacy of blue?light irradiation in the treatment of viper bites. Methods 80 patients with viper bites, admitted to Yichun Hospital of Traditional Chinese Medicine from March 2022 to May 2023, were enrolled as research subjects and divided, based on the treatments they received, into the study group (n = 40) and the control group (n = 40). On the basis of tetanus prevention, snake venom neutralization and the external appli-cation of TCM cataplasm, patients in the study group were treated with blue-light irradiation therapy whereas patients were treated with cefazolin sodium in the control group. The length of stay, the swelling and pain degree of affected limb, inflammatory factor levels and clinical efficacy were compared between the two groups. Results There was no significant difference between the study group and the control group in terms of the length of stay ( t = 1.858, P = 0.067). No significant differences were observed between the two groups in the scores of the swelling and pain degree of affected limbs on day 3 and 6 of treatment, and the levels of white blood cell count (WBC) and C-reactive protein (CRP) on day 6 of treatment (day 3 of treatment: t = 1.670 and 1.868, P= 0.099 and 0.066; day 6 of treatment: t / Z= -1.835, 1.932, 1.783 and 0.924,P= 0.070, 0.057, 0.077 and 0.358). After 7 days of treatment, 30 patients were cured, 9 patients were markedly effective, 1 patient was effective in the study group, which showed no statistically significant difference compared with the control group (Z=-0.450, P= 0.653) - 32 patients cured, 6 patients markedly effective, 2 patients effective. Conclusion Blue-light irradiation can improve symptoms of swelling and pain of affected limbs after viper bites, reduce systemic inflammatory responses, and realize comparable clinical efficacy to that of cefazolin sodium, and thus can be used as an alternative of antibiotics for the treatment of viper bites. |
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