• 椎体压缩性骨折经皮椎体成形术后残余疼痛的危险因素分析
  • Risk Factors for Residual Pain after Percutaneous Vertebroplasty for Vertebral Compression Fracture
  • 先明博,李 晓.椎体压缩性骨折经皮椎体成形术后残余疼痛的危险因素分析[J].中国烧伤创疡杂志,2024,(3):222~225.
    DOI:
    中文关键词:  椎体压缩性骨折  经皮椎体成形术  术后残余疼痛  骨水泥  Logistic回归分析
    英文关键词:Vertebral compression fracture  Percutaneous vertebroplasty  Postoperative residual pain  Bone cement  Logistic regression analysis
    基金项目:
    作者单位
    先明博 473007 河南 南阳, 南阳医学高等专科学校第一附属医院骨科 
    李 晓  
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    中文摘要:
          【摘要】 目的 分析探讨椎体压缩性骨折经皮椎体成形术后残余疼痛的相关危险因素。方法 选取 2021 年2 月至 2022 年 3 月南阳医学高等专科学校第一附属医院收治的 64 例拟行经皮椎体成形术治疗的椎体压缩性骨折患者作为研究对象, 收集患者性别、年龄、体重指数、术前视觉模拟评分法 (VAS) 评分、骨折椎体数量、有无腰背筋膜损伤、有无高血压、有无糖尿病以及手术时间、手术入路方式、骨水泥注入量、骨水泥分布等资料, 并根据经皮椎体成形术后 2 个月是否有残余疼痛将其分为疼痛组与无疼痛组, 多因素 Logistic 回归分析椎体压缩性骨折经皮椎体成形术后残余疼痛的相关危险因素。 结果 经皮椎体成形术后 2 个月, 64 例椎体压缩性骨折患者中 14 例 (21.88%) 患者有残余疼痛, 设为疼痛组, 其余 50 例 (78.12%) 患者无残余疼痛, 设为无疼痛组。单因素分析结果显示, 疼痛组骨折椎体≥2 个、有腰背筋膜损伤、骨水泥呈 O 型分布的患者比例均明显高于无疼痛组 (χ2 = 7.886、7.230、6.328, P = 0.005、0.007、0.012), 骨水泥注入量明显少于无疼痛组 ( t = 7.018, P<0.001)。 多因素 Logistic 回归分析结果显示, 骨折椎体≥2 个、有腰背筋膜损伤、骨水泥注入量少、骨水泥呈 O型分布是椎体压缩性骨折经皮椎体成形术后残余疼痛的独立危险因素 ( 95% CI 为 1.080~160.958、1.008~104.097、0.025~0.756、1.089~135.537, P= 0.043、0.049、0.023、0.042)。结论 椎体压缩性骨折经皮椎体成形术后残余疼痛的发生与骨折椎体数量、有无腰背筋膜损伤、骨水泥注入量及骨水泥分布情况密切相关。
    英文摘要:
          【Abstract】 Objective To study the risk factors for residual pain after percutaneous vertebroplasty for vertebral compression fracture. Methods 64 patients with vertebral compression fracture, admitted to The First Affiliated Hospital of Nanyang Medical College for percutaneous vertebroplasty between February 2021 and March 2022, were selected as research subjects, and patients’ data, including sex, age, body mass index, preoperative visual analogue scale ( VAS) score, number of fractured vertebra, with thoracolumbar fascia injury or not, with hypertension and diabetes or not, operation time, surgical approach, injection volume and distribution of bone cement were collected. Based on whether the residual pain occurred two months after percutaneous vertebroplasty, the patients were divided into the pain group and the non-pain group. Multivariate Logistic regression analysis was performed to analyze the risk factors for residual pain after percutaneous vertebroplasty for vertebral compression fracture. Results Two months after percutaneous vertebroplasty, 14 cases of the 64 patients (21.88%) suffered residual pain, being set as the pain group, and the other 50 cases (78.12%) had no residual pain, being set as the non-pain group. The results of univariate analysis showed that the proportions of patients with more than two fractured vertebras, with thoracolumbar fascia injury, type-O bone cement distribution were significantly higher in the pain group compared with the non-pain group (χ2 = 7.886, 7.230 and 6.328, P= 0.005, 0.007 and 0.012), while the injection volume of bone cement was significantly less in the pain group (t = 7.018, P<0.001). Multivariate Logistic regres-sion analysis showed that with more than two fractured vertebras, with thoracolumbar fascia injury, low injection volume of bone cement, and type-O bone cement distribution were independent risk factors for residual pain after percutaneous vertebroplasty for vertebral compression fracture (95%CI: 1.080-160.958, 1.008-104.097, 0.025-0.756, 1.089-135.537,P= 0.043, 0.049, 0.023 and 0.042). Conclusion The occurrence of residual pain after percutaneous vertebroplasty for vertebral compression fracture is closely associated with such factors as the number of fractured vertebra, with thoracolumbar fascia injury or not, injection volume and distribution of bone cement.