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二氧化碳点阵激光在慢性创面治疗中的应用效果分析
Clinical Efficacy of Fractional CO2 Laser in the Treatment of Chronic Wounds

刘移峰,刘平洪.二氧化碳点阵激光在慢性创面治疗中的应用效果分析[J].中国烧伤创疡杂志,2024,(4):256~258.

DOI：

英文关键词:Fractional CO2 laser Chronic wound Granulation tissue Edema Wound healing

基金项目:

作者	单位
刘移峰	510800 广东广州, 广州市中西医结合医院烧伤与创面修复科
刘平洪

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中文摘要:

【摘要】目的探讨分析二氧化碳点阵激光在慢性创面治疗中的应用效果。方法选取 2022 年11月至2023年10 月广州市中西医结合医院收治的64例慢性创面患者作为研究对象, 按照不同治疗方法将其分为观察组(32例)和对照组(32例), 观察组患者局部创面采用敷料外敷联合二氧化碳点阵激光治疗, 对照组患者局部创面单纯采用敷料外敷治疗, 对比观察两组患者创面水肿、肉芽组织生长及愈合情况。结果治疗第1、3、7天,观察组患者创面水肿情况与对照组均无明显差异(Z= -0.254、-0.635、-0.308, P = 0.799、0.525、0.758); 治疗第7、14、21 天, 观察组患者创面肉芽组织生长情况均明显优于对照组(Z = -5.051、-5.055、-4.720, P 均<0.001); 治疗第7、14、21 天, 观察组患者创面愈合率均明显高于对照组 (t = 7.818、7.217、7.171, P 均<0.001)。结论在敷料外敷基础上应用二氧化碳点阵激光治疗慢性创面, 能够有效促进创面肉芽组织生长, 加快创面愈合。

英文摘要:

【Abstract】 Objective To analyze the clinical efficacy of fractional CO2 laser in the treatment of chronic wounds.Methods 64 patients with chronic wounds, admitted to Guangzhou Hospital of Integrated Traditional and Western Medicine, from November 2022 to October 2023 were enrolled as the research subjects and divided into the study group (n = 32) and the control group (n=32) according to the different treatment methods they received. The local wounds of patients in the study group were treated with dressing application combined with fractional CO2 laser treatment, whereas the local wounds of patients in the control group were treated with dressing application alone. Wound edema, granulation tissue growth, and healing status were observed and compared between the two groups. Results Respectively on day 1, 3 and 7 of treatment, there was no significant difference between the study group and the control group in terms of wound edema (Z=-0.254, -0.635 and -0.308, P= 0.799, 0.525 and 0.758). Respectively on day 7, 14 and 21 of treatment, the growth condition of granulation tissues in the study group was significantly better than that in the control group (Z=- 5.051, -5.055 and -4.720, all P<0.001), and the wound healing rates of patients in the study group were significantly higher than those in the control group (t=7.818, 7.217 and 7.171, allP<0.001). Conclusion The application of fractionalCO2 laser combined with dressing application in the treatment of chronic wounds can effectively promote granulation tissue growth and accelerate wound healing.