• 纤支镜肺泡灌洗在创伤致急性呼吸窘迫综合征合并感染机械通气患者中的应用效果分析
  • Effect of bronchoscopic alveolar lavage in patients on mechanical ventilation with trauma-induced acute respiratory distress syndrome
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    中文关键词:  创伤  急性呼吸窘迫综合征  纤支镜  肺泡灌洗  机械通气
    英文关键词:Trauma  acute respiratory distress syndrome  Fiberscope  alveolar lavage  Mechanical ventilation
    基金项目:
    作者单位邮编
    张占胜* 渑池县人民医院急诊科 河南三门峡 472400 472400
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    中文摘要:
          目的 分析纤支镜肺泡灌洗在创伤致急性呼吸窘迫综合征合并感染机械通气患者中的应用效果。方法 选取2021年6月至2024年6月收治的122例创伤致急性呼吸窘迫综合征合并感染患者为研究对象。按照不同处理方法将其分为研究组与对照组,每组61例。对照组患者进行常规机械通气,研究组患者在常规机械通气基础上应用纤支镜肺泡灌洗,对比两组患者炎症因子水平、血氧指标、肺功能指标、机械通气时间、重症监护病房住院时间、气道相关并发症以及死亡情况。结果 治疗7 d后,研究组患者PCT、CRP、IL-6、sTREM-1水平均低于对照组(P<0.05);治疗7 d后,研究组患者PaO2、PaO2/FiO2均高于对照组(P<0.05);治疗7 d后,研究组患者Cdyn高于对照组,WOB、Raw低于对照组(P<0.05);研究组患者机械通气时间、重症监护病房住院时间明显短于对照组(P<0.05);研究组患者气道相关并发症发生率明显低于对照组(P<0.05)。结论 给予创伤致急性呼吸窘迫综合征合并感染患者应用机械通气的基础上进行纤支镜肺泡灌洗,能够有效减轻炎症反应,提高肺部功能,降低危重症患者气道相关并发症发生风险,加快患者康复。
    英文摘要:
          【Abstract】 Objective To analyze the effect of fiberoptic alveolar lavage in patients with trauma-induced acute respiratory distress syndrome complicated with mechanical ventilation. Methods A total of 122 patients with trauma-induced acute respiratory distress syndrome (ARDS) co-infection who were admitted from June 2021 to June 2024 were enrolled. According to different treatment methods, they were divided into study group and control group, with 61 cases in each group. The patients in the control group underwent conventional mechanical ventilation, and the patients in the study group were treated with bronchoscopic alveolar lavage on the basis of conventional mechanical ventilation, and the levels of inflammatory factors, blood oxygen indexes, pulmonary function indexes, duration of mechanical ventilation, length of stay in intensive care unit, airway-related complications and mortality were compared between the two groups. Results After 7 days of treatment, the levels of PCT, CRP, IL-6 and sTREM-1 in the study group were lower than those in the control group (P<<0.05), and after 7 days of treatment, the levels of PaO2 and PaO2/FiO2 in the study group were higher than those in the control group (P<0.05). The length of stay in the intensive care unit was significantly shorter than that in the control group (P<0.05), and the incidence of airway-related complications in the study group was significantly lower than that in the control group (P<0.05). Conclusion Bronchoscopic alveolar lavage on the basis of mechanical ventilation in patients with trauma-induced acute respiratory distress syndrome and infection can effectively reduce inflammation, improve lung function, reduce the risk of airway-related complications in critically ill patients, and accelerate the recovery of patients