【Abstract】 Objective To analyze the effect of fiberoptic alveolar lavage in patients with trauma-induced acute respiratory distress syndrome complicated with mechanical ventilation. Methods A total of 122 patients with trauma-induced acute respiratory distress syndrome (ARDS) co-infection who were admitted from June 2021 to June 2024 were enrolled. According to different treatment methods, they were divided into study group and control group, with 61 cases in each group. The patients in the control group underwent conventional mechanical ventilation, and the patients in the study group were treated with bronchoscopic alveolar lavage on the basis of conventional mechanical ventilation, and the levels of inflammatory factors, blood oxygen indexes, pulmonary function indexes, duration of mechanical ventilation, length of stay in intensive care unit, airway-related complications and mortality were compared between the two groups. Results After 7 days of treatment, the levels of PCT, CRP, IL-6 and sTREM-1 in the study group were lower than those in the control group (P<<0.05), and after 7 days of treatment, the levels of PaO2 and PaO2/FiO2 in the study group were higher than those in the control group (P<0.05). The length of stay in the intensive care unit was significantly shorter than that in the control group (P<0.05), and the incidence of airway-related complications in the study group was significantly lower than that in the control group (P<0.05). Conclusion Bronchoscopic alveolar lavage on the basis of mechanical ventilation in patients with trauma-induced acute respiratory distress syndrome and infection can effectively reduce inflammation, improve lung function, reduce the risk of airway-related complications in critically ill patients, and accelerate the recovery of patients |