【Abstract】 Objective To analyze the efficacy of moist burn ointment combined with hemorrhoidal fistula lotion in the postoperative wound treatment of perianal abscess. Methods A total of 130 patients who were admitted from May 2022 to May 2024 who were to undergo radical perianal abscess resection were selected as the study subjects, and they were divided into study group and control group according to different postoperative wound treatment methods, with 65 cases in each group. After perianal abscess radical resection, on the basis of hemorrhoidal fistula lotion fumigation sitz bath, moist burn ointment was applied to the wound of the patients in the study group, and anal Tai ointment was applied to the wound of the patients in the control group, and the serum inflammatory index level, growth factor level and pain score, complete wound epithelialization time and skin scar hyperplasia after healing were compared between the two groups. Results On the 7th and 14th days after surgery, the levels of C-reactive protein, amyloid A and tumor necrosis factor-α in the study group were significantly lower than those in the control group (P<0.05), the levels of epidermal growth factor and vascular endothelial growth factor in the study group were significantly higher than those in the control group (P<0.05) on the 7th and 14th days after surgery, the wound pain scores in the study group were significantly lower than those in the control group (P<0.05) on the 3rd and 7th days after surgery, and the complete wound epithelialization time in the study group was significantly shorter than that in the control group. The scar score of the healed skin was significantly lower than that of the control group (P<0.05). Conclusion After radical perianal abscess, applying moist burn ointment to the wound on the basis of fumigation and sitz bath with hemorrhoidal fistula lotion can significantly reduce the level of inflammatory indicators, increase the level of growth factors, reduce the degree of pain, accelerate the complete epithelialization of the wound, and improve the scar hyperplasia. |