• 肛周脓肿术后创面应用湿润烧伤膏联合痔瘘洗剂治疗的临床研究
  • A clinical study on the treatment of wounds after perianal abscess with moist burn ointment combined with hemorrhoidal fistula lotion
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    中文关键词:  【关键词】湿润烧伤膏  痔瘘洗剂  肛周脓肿  创面  炎症  疼痛  瘢痕增生
    英文关键词:【Keywords】moist burn ointment  hemorrhoidal fistula lotion  perianal abscess  Wound  Inflammation  Pain  Scarring
    基金项目:
    作者单位邮编
    王凤栖* 南阳市第一人民医院 473000
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    中文摘要:
          【摘要】 目的 分析肛周脓肿术后创面应用湿润烧伤膏联合痔瘘洗剂治疗的疗效。方法 选取2022年5月至2024年5月收治的130例拟行肛周脓肿根治术治疗的患者为研究对象,按照术后创面不同处理方法将其分为研究组与对照组,每组65例。肛周脓肿根治术后在痔瘘洗剂熏蒸坐浴的基础上,在研究组患者创面涂抹湿润烧伤膏,对照组患者创面涂抹肛泰软膏,比较两组患者血清炎症指标水平、生长因子水平及疼痛评分、创面完全上皮化时间及愈后皮肤瘢痕增生情况。结果 术后第7、14天,研究组患者C-反应蛋白、淀粉样蛋白A、肿瘤坏死因子-α水平明显低于对照组(P<0.05);术后第7、14天,研究组患者表皮生长因子、血管内皮生长因子水平明显高于对照组(P<0.05);术后第3、7天,研究组患者创面疼痛评分明显低于对照组(P<0.05);研究组患者创面完全上皮化时间明显短于对照组、愈后皮肤瘢痕评分明显低于对照组(P<0.05)。结论 肛周脓肿根治术后在痔瘘洗剂熏蒸坐浴的基础上,创面涂抹湿润烧伤膏,可明显降低炎症指标水平、提高生长因子水平、减轻疼痛程度、加快创面完全上皮化、改善瘢痕增生情况。
    英文摘要:
          【Abstract】 Objective To analyze the efficacy of moist burn ointment combined with hemorrhoidal fistula lotion in the postoperative wound treatment of perianal abscess. Methods A total of 130 patients who were admitted from May 2022 to May 2024 who were to undergo radical perianal abscess resection were selected as the study subjects, and they were divided into study group and control group according to different postoperative wound treatment methods, with 65 cases in each group. After perianal abscess radical resection, on the basis of hemorrhoidal fistula lotion fumigation sitz bath, moist burn ointment was applied to the wound of the patients in the study group, and anal Tai ointment was applied to the wound of the patients in the control group, and the serum inflammatory index level, growth factor level and pain score, complete wound epithelialization time and skin scar hyperplasia after healing were compared between the two groups. Results On the 7th and 14th days after surgery, the levels of C-reactive protein, amyloid A and tumor necrosis factor-α in the study group were significantly lower than those in the control group (P<0.05), the levels of epidermal growth factor and vascular endothelial growth factor in the study group were significantly higher than those in the control group (P<0.05) on the 7th and 14th days after surgery, the wound pain scores in the study group were significantly lower than those in the control group (P<0.05) on the 3rd and 7th days after surgery, and the complete wound epithelialization time in the study group was significantly shorter than that in the control group. The scar score of the healed skin was significantly lower than that of the control group (P<0.05). Conclusion After radical perianal abscess, applying moist burn ointment to the wound on the basis of fumigation and sitz bath with hemorrhoidal fistula lotion can significantly reduce the level of inflammatory indicators, increase the level of growth factors, reduce the degree of pain, accelerate the complete epithelialization of the wound, and improve the scar hyperplasia.