• 再生医疗技术在慢性难愈合性创面治疗中的研究
  • tudy on regenerative medical technology in the treatment of chronic refractory wounds
  • DOI:
    中文关键词:  慢性难愈合性创面  再生医疗技术  MEBO;规范化换药;TIME原则
    英文关键词:Chronic refractory wounds  Regenerative medical technology  MEBO  Standardized dressing change  TIME principle
    基金项目:
    作者单位邮编
    焦睿* 乌海市第三人民医院 016030
    周荣海 乌海市第三人民医院 
    何艳春 乌海市第三人民医院 
    孔德才 乌海市第三人民医院 
    沈一曼 乌海市第三人民医院 
    宋娜 乌海市第三人民医院 
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    中文摘要:
          目的:探讨再生医疗技术在慢性难愈合性创面的临床治疗效果。方法:选取海南区人民医院2023年1月至2024年9月收治符合的40例慢性创面作为研究对象,并按照随机法将其随机分为基础换药组和MEBO组各20例,基础换药组采取凡士林油纱治疗,MEBO组采取MEBO治疗,对比观察创面肉芽组织、创面面积、创面愈合率治疗前、第3天、第7天、第21天生长情况。结果:经过3周治疗,两组组内采取独立样本t检验,MEBO组肉芽组织前后对比(t=1.731、t=3.644、P=0.012、P=0.000)、创面面积治疗第21天(P=0.000)、创面愈合率第3天与第21天对比(P=0.001),且MEBO组小于基础换药组,差异具有统计学意义(P<0.05),得出MEBO组治疗效果突出;观察两组患者疗效,总有效率高于基础换药组,差异具有统计学意义P<0.05(P=0.004),Χ2=13.192a。讨论:MEBO组比基础换药组有效提高创面愈合,缩短愈合时间,且临床操作简单,以及临床规范化治疗,值得临床推广应用。
    英文摘要:
          【 Abstract 】 Objective: To explore the clinical therapeutic effect of regenerative medical technology on chronic refractory wounds. Methods: 40 cases of chronic wounds treated in Hainan District People's Hospital from January 2023 to September 2024 were selected as the research object, and randomly divided into basic dressing change group and MEBO group, with 20 cases in each group. The basic dressing change group was treated with vaseline gauze, while MEBO group was treated with MEBO. The granulation tissue, wound area and wound healing rate of the wound were compared and observed before treatment, the third day, the seventh day and the 21st day. Results: After 3 weeks of treatment, independent sample T test was taken in the two groups. The granulation tissue in MEBO group was compared before and after (t=1.731, t=3.644, P=0.012, P=0.000), the wound area was treated on the 21st day (P=0.000), and the wound healing rate was compared on the 3rd and 21st days (p = Observing the curative effect of the two groups, the total effective rate was higher than that of the basic dressing change group, and the difference was statistically significant (P < 0.05 (P = 0.004), χ 2 = 13.192a). Discussion: MEBO group can effectively improve the wound healing and shorten the healing time compared with the basic dressing change group, and it is simple in clinical operation and standardized in clinical treatment, which is worthy of clinical application.