| Objective: To explore and analyze the clinical efficacy of MEBO Moist Exposed Burn Ointment in the treatment of facial abrasions in children. Methods: A total of 116 children with facial abrasions admitted to the Department of Plastic Surgery of Nanyang Nanshi Hospital from January 2023 to July 2024 were included and screened according to the inclusion and exclusion criteria. They were randomly divided into an experimental group and a control group using a random number table, with 58 cases in each group. The experimental group was treated with MEBO Moist Exposed Burn Ointment for dressing changes, while the control group was treated with the traditional method of cleaning with normal saline and covering with oil gauze. The healing time of the wound, the number of dressing changes, and the pain index were observed in both groups. Inflammatory factors and pigmentation were also measured. Results: (1) The healing time of the wound in the experimental group was significantly shorter than that in the control group (t = 5.132, P < 0.05), and the number of dressing changes was also reduced (t = 9.663, P < 0.05), with statistically significant differences. (2) The pain index during dressing changes in the experimental group was significantly lower than that in the control group at the time of injury, on the 1st, 3rd, 5th, 10th, and 15th days (t = 0.235, 4.056, 1.572, 2.313, 1.826, 1.167, P = 0.478, 0.001, 0.001, 0.001, 0.001, 0.001). (3) Before treatment, there were no statistically significant differences in the levels of serum α-MSH, IL-13, IL-18, and IL-33 between the two groups (t = 0.893, 0.443, 4.692, 9.725, P = 0.565, 0.659, 0.419, 0.671). After 48 hours of treatment, the levels of serum α-MSH, IL-13, IL-18, and IL-33 in both groups were lower than those before treatment, and the levels in the experimental group were lower than those in the control group (t = 4.972, 8.074, 4.371, 7.072, P = 0.001, 0.001, 0.001, 0.001). (4) The melanin intensity in the control group was significantly higher than that in the experimental group (t = 4.637, P = 0.001). Conclusion: Compared with the traditional therapy, MEBO Moist Exposed Burn Ointment in the treatment of facial abrasions in children has the advantages of shortening the healing time, reducing pain, and decreasing pigmentation. |
